Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10008995
Fusion event
HBV-DPY19L2P1 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
S protein|Polymerase|large S protein|middle S protein|
Start
707
Orient
-
Integrated sequence
CCATCCCATCATCCTGGGCTTTCGGAAAATTCCTATGGGAGTGGGCCTCAGCCCGTTTCTCCTGGCTCAGTTTACTAGTGCCATTTGTTCAGTGGTTCGT| |AGGGCTTTCCCCCACTGTTTGGCTTTCAGTTATATGGATGATGTGGTATTGGGGGCCAAGTCTGTACAGCATCTTGAGTCCCTTTTTACCGCTGTTACCA
Host Sequence
Chromosome
chr7
Cytoband
p14.2
Reference genome
Start
End
35124333/35084721 (Hg38)
Orient
-
Location type
ncRNA_intronic
Fragile sites / regions
Target gene
Nearest miRNA
hsa-mir-1183/Upstream/143887; hsa-mir-10399/Downstream/1834636;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/46525, chr7-CpG: 97/Downstream/101030
Upstream sequence
GTAAAATTGTGTAGAATTCTCAGATAGTAATCAGACAACAGAGGCTTCAGTTGTGAGAGTTAGAATCTGAGAAACAAGCTCCAGGTACACAGGATAGGAA
Downstream sequence
tttctttaatatattgctggattcatttgttgcaattttacttaaaaatttcacatatgtgttcatgataaattttgattggttgtttccttttattgta
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.