Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10009001
Fusion event
HBV-CYP3A4 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
Polymerase|
Start
861
Orient
+
Integrated sequence
GCCAAGTCTGTACAGCATCTTGAGTCCCTTTTTACCGCTGTTACCAATTTTCTTTTGTCTTTGGGTATACATTTAAACCCTAACAAAACAAAGAGATGGG| |GTTACTCTCTAAATTTTATGGGTTATGTCATTGGATGTTATGGGTCCTTGCCACAAGAACACATCATACAAAAAATCAAAGAATGTTTTAGAAAACTTCC
Host Sequence
Chromosome
chr7
Cytoband
q22.1
Reference genome
Start
End
99377337/99779714 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
Target gene
miRNAs that regulate target gene
Nearest miRNA
hsa-mir-10525/Upstream/370450; hsa-mir-10399/Downstream/313846;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/162452, chr7-CpG: 76/Downstream/139265
Upstream sequence
ttgggaggccgaggtgggcagatcacctgaggtcaggaattcgagaccagcctagccaacatggcaaaaccccatatctactaaaaatacaaaaattagc
Downstream sequence
CTTTATGGCGCTCACAAAGTTTGCACATCAAGTTCTGAGCATCAGGTTGCTGATCTACCTGAGATTTGGGCTGTTCAACTGAGGCAAACCTGAGGTTCCT
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.