Basic Information
VIS ID
TVIS10009013
Fusion event
HBV-LOC102724687 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
30271481
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Region type
X protein|Polymerase|
Start
1602
Orient
-
Integrated sequence
CTGCCGTTCCGACCGACCACGGGGCGCACCTCTCTTTACGCGGACTCCCCGTCTGTGCCTTCTCATCTGCCGGACCGTGTGCACTTCGCTTCACCTCTGC| |ACGTCGCATGGAGACCACCGTGAACGCCCACCAAATATTGCCCAAGGTCTTACATAAGAGGACTCTTGGACTCTCAGCAATGTCAACGACCGACCTTGAG
Host Sequence
Chromosome
chr8
Cytoband
q13.1
Reference genome
GRCh37/hg19
Start
67305653/66393418 (Hg38)
End
67305653/66393418 (Hg38)
Orient
+
Location type
Intronic
Target gene
LOC102724687
Nearest miRNA
hsa-mir-124-1/Upstream/2014161; hsa-mir-10400/Downstream/8155125;
Nearest TSS
ENST00000518652/Upstream/200709; ENST00000320270/Downstream/35559;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/215691, chr8-CpG: 112/Downstream/35143
Nearby gene
LINC00967(-196099) ; RRS1-AS1(+26169) ;
Upstream sequence
taatgaactcgataactctatattgttaagatagcaactccccaaattaaactatagtcaatacagtcccaatcaaaatctcagcagtttttctttatac
Downstream sequence
ATTGCTGATCTTTACTCTCACAGGCACTGACAGTTGCCTGGCAGGATCAAGGGAGAGCTTATTAAGAGGGAGGGTTTTTTGTCATTACATATGGTTGGAT
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
Curate