Basic Information
VIS ID
TVIS10009019
Fusion event
HBV-chr9 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
30271481
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Region type
X protein|
Start
1792
Orient
-
Integrated sequence
CGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCAT| |AAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTG
Host Sequence
Chromosome
chr9
Cytoband
p11.2
Reference genome
GRCh37/hg19
Start
47180646/41775105 (Hg38)
End
47180646/41775105 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-mir-101-2/Upstream/541270; hsa-let-7a-1/Downstream/29034870;
Nearest TSS
ENST00000422679/Upstream/76033; ENST00000496386/Downstream/124839;
Nearest CpG islands
None/Target, chr9-CpG: 64/Upstream/94648, chr9-CpG: 30/Downstream/3620
Nearby gene
LINC01189(-347327) ;
Upstream sequence
AATGCAATTTATGATATGTCAAGTAGACCTCAATAGAGCTGTTTTAAAACATACAACAGAATTTCCCGCAACCCAACCACACCACCCGCGCCATCACACG
Downstream sequence
GACCCAGAGAGCCCATGGGCAGACAGTCTTGGTGCTGCATGCCCGGGCTTAAACCAGCAAGCCTGATTCTGAATGTCCACAAGCTCTTGGCTGGTGGGGC
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
Curate