VISDB Viral Integration Site DataBase

VIS ID

TVIS10009044

Fusion event

HBV-SHISA6 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

X protein|

Start

1752

Orient

-

Integrated sequence

TACATAAGAGGACTCTTGGACTCTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGA| |GATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTT

Chromosome

chr17

Cytoband

p12

Reference genome

Start

End

11366196/11462879 (Hg38)

Orient

-

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-620 ; hsa-mir-1270 ; hsa-mir-5196-5p ; hsa-mir-6797-5p ; hsa-mir-4747-5p ; hsa-mir-1249-5p ; hsa-mir-4683 ; hsa-mir-4722-5p ; hsa-mir-1286 ; hsa-mir-873-5p ; hsa-mir-4708-5p ; hsa-mir-9500 ; hsa-mir-4459 ; hsa-mir-4779 ; hsa-mir-6763-5p ; hsa-mir-3150a-3p ; hsa-mir-491-5p ; hsa-mir-7847-3p ; hsa-mir-92a-2-5p ; hsa-mir-6825-5p ; hsa-mir-939-5p ; hsa-mir-1343-5p ; hsa-mir-3175 ; hsa-mir-7106-5p ; hsa-mir-8085 ; hsa-mir-6731-5p ; hsa-mir-6851-5p ; hsa-mir-3689d ; hsa-mir-766-5p ; hsa-mir-3665 ; hsa-mir-6134 ; hsa-mir-3928-3p ; hsa-mir-6777-5p ; hsa-mir-6889-5p ; hsa-mir-194-3p ; hsa-mir-5693 ; hsa-mir-2278 ; hsa-mir-6875-3p ; hsa-mir-6502-5p ; hsa-mir-1301-5p ; hsa-mir-4778-3p ; hsa-mir-26a-2-3p ; hsa-mir-26a-1-3p ; hsa-mir-6731-3p ; hsa-mir-499b-5p ; hsa-mir-4494 ; hsa-mir-506-5p ; hsa-mir-892c-5p ; hsa-mir-3680-5p ; hsa-mir-6741-3p ; hsa-mir-6867-3p ; hsa-mir-6749-3p ; hsa-mir-6826-3p ; hsa-mir-1298-5p ; hsa-mir-7110-3p ; hsa-mir-4685-3p ; hsa-mir-4287 ; hsa-mir-7113-3p ; hsa-mir-4469 ; hsa-mir-205-5p ; hsa-mir-6769b-3p ; hsa-mir-4723-3p ; hsa-mir-3183 ; hsa-mir-5193 ; hsa-mir-2276-5p ; hsa-mir-6892-3p ; hsa-mir-6795-3p ; hsa-mir-6887-3p ; hsa-mir-502-5p ; hsa-mir-1915-5p ; hsa-mir-6841-3p

Nearest miRNA

hsa-mir-1253/Upstream/3275875; hsa-mir-10226/Downstream/619020;

Nearest TSS

Nearest CpG islands

None/Target, chr17-CpG: 26/Upstream/220780, chr17-CpG: 32/Downstream/94875

Upstream sequence

accatgcctggctaatttttgtatttttagtggagatgaggtttcaccattttggccaggctggtctcgaacttctgacttcaagtgatctgcccacctt

Downstream sequence

ggcctcccaaagtgctgggattatagcgtgTTATCCAGTGTGTTATCCATTGAGGTAGGATAAAAAACGAAGAAGCGTACAAATGCAAATTTTGTCTTTG