VISDB Viral Integration Site DataBase

VIS ID

TVIS10009048

Fusion event

HBV-ZFR integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

X protein|

Start

1765

Orient

+

Integrated sequence

TCTTGGACTCTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAG| |GTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGT

Chromosome

chr5

Cytoband

p13.3

Reference genome

Start

End

32416121/32416016 (Hg38)

Orient

+

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-34a-5p ; hsa-mir-484 ; hsa-mir-8061 ; hsa-mir-4760-5p ; hsa-mir-376a-5p ; hsa-mir-545-3p ; hsa-mir-3120-3p ; hsa-mir-5700

Nearest miRNA

hsa-mir-10397/Upstream/21541; hsa-mir-103a-1/Downstream/3731876;

Nearest TSS

Nearest CpG islands

None/Target, chr5-CpG: 87/Upstream/102653, chr5-CpG: 122/Downstream/27631

Upstream sequence

aacaccaaaagcaatggcaacaaaagccaaaattgacaaatgggatctaattaaactcaagagcttctgcacagcaaaagaaactaccatcagagtgtac

Downstream sequence

gtatgatggtgtgatcatggctcactgcaacctcaaactcctggactcaagtgatcctcccacctcagccactcaagtagAACTTATCTGCTTATGAAAT