PIK3C2G _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10009054
Fusion event
HBV-PIK3C2G integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
30271481
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Region type
S protein|Polymerase|large S protein|middle S protein|
Start
459
Orient
-
Integrated sequence
TTGTCCTGGTTATCGCTGGATGTGTCTGCGGCGTTTTATCATCTTCCTCTTCATCCTGCTGCTATGCCTCATCTTCTTGTTGGTTCTTCTGGACTATCAA| |GGTATGTTGCCCGTTTGTCCTCTAATTCCAGGATCCTCAACAACCAGCACGGGACCATGCCGGACCTGCATGACTACTGCTCAAGGAACCTCTATGTATC
Host Sequence
Chromosome
chr12
Cytoband
p12.3
Reference genome
GRCh37/hg19
Start
18786872/18633938 (Hg38)
End
18786872/18633938 (Hg38)
Orient
-
Location type
Intronic
Target gene
PIK3C2G
Nearest miRNA
hsa-mir-1244-3/Upstream/960544; hsa-let-7i/Downstream/5578483;
Nearest TSS
ENST00000382841/Upstream/262757; ENST00000536931/Downstream/61099;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/2722338, chr12-CpG: 131/Downstream/495453
Upstream sequence
ttatgattcggtttagaggaactaagatctctaggctggtagtgtgtaagggtgtaggaacaggaaacaaaaatttgcttgttactcactgggcataata
Downstream sequence
gtgtgtggtgccattcccatttccacccctttattcctgtacctgtgaatcttggctatcagagaaagcgccatatattggatgctggttcagagcatac
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
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