VISDB Viral Integration Site DataBase

VIS ID

TVIS10009059

Fusion event

HBV-VRK1 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

X protein|precore/core protein|

Start

1816

Orient

+

Integrated sequence

CTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCA| |TGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCC

Chromosome

chr14

Cytoband

q32.2

Reference genome

Start

End

97297038/96830701 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-24-3p ; hsa-mir-4693-3p ; hsa-mir-4694-3p ; hsa-mir-3662

Nearest miRNA

hsa-mir-1260a/Upstream/1692715; hsa-mir-1185-1/Downstream/3278718;

Nearest TSS

Nearest CpG islands

None/Target, chr14-CpG: 35/Upstream/32799, chr14-CpG: 54/Downstream/202567

Upstream sequence

CCTTTTGGGAGGCATGTTTTCTTATGTACTTTTCTAAAGGGATTTTTTTTCTCTTTAAAAATACCAACTTAGTGTGGCACTAGGCTTTGATCCATTTTTG

Downstream sequence

TTGCTGAGTTTCGTATGCAGCCAGTTTTCCCTTATATGCAATTAGTTTTAGATAGTCTGGTTCAGGGTGAGTGTATGTCATTCTCTAGATCCCACTCTTC