VISDB Viral Integration Site DataBase

VIS ID

TVIS10009073

Fusion event

HBV-UST integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

X protein|

Start

1795

Orient

-

Integrated sequence

CCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAA| |TTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCT

Chromosome

chr6

Cytoband

q25.1

Reference genome

Start

End

149114797/148793661 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-1-3p ; hsa-mir-335-5p ; hsa-mir-98-5p ; hsa-mir-1296-5p ; hsa-mir-6780a-5p ; hsa-mir-6779-5p ; hsa-mir-3689c ; hsa-mir-3689b-3p ; hsa-mir-3689a-3p ; hsa-mir-30b-3p ; hsa-mir-1273h-5p ; hsa-mir-3978 ; hsa-mir-6778-5p ; hsa-mir-1233-5p ; hsa-mir-486-3p ; hsa-mir-6799-5p ; hsa-mir-6883-5p ; hsa-mir-6785-5p ; hsa-mir-4728-5p ; hsa-mir-149-3p ; hsa-mir-7106-5p ; hsa-mir-449b-5p ; hsa-mir-449a ; hsa-mir-34c-5p ; hsa-mir-34a-5p ; hsa-mir-6851-5p ; hsa-mir-3689d ; hsa-mir-6134 ; hsa-mir-423-5p ; hsa-mir-3184-5p ; hsa-mir-6743-5p ; hsa-mir-194-3p ; hsa-mir-4688 ; hsa-mir-5692b ; hsa-mir-5692c ; hsa-mir-641 ; hsa-mir-3617-5p ; hsa-mir-5692a ; hsa-mir-154-5p ; hsa-mir-374a-5p ; hsa-mir-369-3p ; hsa-mir-374b-5p ; hsa-mir-149-5p ; hsa-mir-660-3p ; hsa-mir-5196-3p ; hsa-mir-5193 ; hsa-mir-6765-3p

Nearest miRNA

hsa-mir-10398/Upstream/8109778; hsa-mir-1202/Downstream/2309014;

Nearest TSS

Nearest CpG islands

None/Target, chr6-CpG: 120/Upstream/45022, chr6-CpG: 97/Downstream/83562

Upstream sequence

GACccccccaatttcttctctggcccctccattcctcctgaagtcagatttgcatttctaacagcctcctgaaaatctgagagtatgtcacagagatata

Downstream sequence

ggactttttcagctccattatcatcttgtgggcccatcattgtatatttggctcatGACTGCaattggaataatatagtatgtctccttctgagttcgtg