hsa-mir-130b-3p _LIHC.png
PPP1R9A _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10009077
Fusion event
HBV-PPP1R9A integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
30271481
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Region type
Polymerase|
Start
2481
Orient
+
Integrated sequence
TCCCTCGCCTCGCAGACGAAGGTCTCAATCGCCGCGTCGCAGAAGATCTCAATCTCGGGAATCTCAATGTTAGTATTCCTTGGACTCATAAGGTGGGGAA| |CTTTACTGGGCTTTATTCTTCTACTGTACCTGTCTTTAATCCTCATTGGAAAACACCATCTTTTCCTAATATACATTTACACCAAGACATTATCAAAAAA
Host Sequence
Chromosome
chr7
Cytoband
q21.3
Reference genome
GRCh37/hg19
Start
94607579/94978267 (Hg38)
End
94607579/94978267 (Hg38)
Orient
+
Location type
Intronic
Target gene
PPP1R9A
miRNAs that regulate target gene
hsa-mir-335-5p ; hsa-mir-130b-3p ; hsa-mir-33a-5p ; hsa-mir-181a-5p ; hsa-mir-3121-3p
Nearest miRNA
hsa-mir-10525/Upstream/1261262; hsa-mir-10399/Downstream/1241395;
Nearest TSS
ENST00000635602/Upstream/68184; ENST00000608730/Downstream/236065;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/70102, chr7-CpG: 19/Downstream/346190
Upstream sequence
gtggttgcaggggttgagtggacaaagagggatgaataggcagaacacaaaggattttgagggtagttaaaatactctatataataatataatggtggat
Downstream sequence
TGAGATTGAATTGTACCAAAAAGCCAAATTATGGCTATCTACTAAATATAGAGCCTGCATGTTTTTAATTGATTTATGATTATAGAGTAGACTAAATTTT
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
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