VISDB Viral Integration Site DataBase

VIS ID

TVIS10009082

Fusion event

HBV-DCAF12 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

X protein|

Start

1802

Orient

-

Integrated sequence

GCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCT| |GCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGC

Chromosome

chr9

Cytoband

p13.3

Reference genome

Start

End

34117380/34117382 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-29c-3p ; hsa-mir-128-3p ; hsa-mir-30b-5p ; hsa-mir-7-5p ; hsa-mir-615-3p ; hsa-mir-92a-3p ; hsa-mir-6728-3p ; hsa-mir-8485 ; hsa-mir-3591-5p ; hsa-mir-580-3p ; hsa-mir-4670-3p ; hsa-mir-4738-3p ; hsa-mir-4280 ; hsa-mir-4496 ; hsa-mir-142-3p ; hsa-mir-216b-5p ; hsa-mir-377-3p ; hsa-mir-7110-3p ; hsa-mir-342-3p ; hsa-mir-6736-3p ; hsa-mir-135a-3p ; hsa-mir-186-5p ; hsa-mir-3133 ; hsa-mir-33a-3p ; hsa-mir-380-5p ; hsa-mir-4766-3p ; hsa-mir-563 ; hsa-mir-592 ; hsa-mir-597-5p ; hsa-mir-659-3p ; hsa-mir-668-3p ; hsa-mir-6740-5p ; hsa-mir-6757-5p ; hsa-mir-6867-5p

Nearest miRNA

hsa-mir-101-2/Upstream/649447; hsa-let-7a-1/Downstream/1490712;

Nearest TSS

Nearest CpG islands

None/Target, chr9-CpG: 64/Upstream/67765, chr9-CpG: 66/Downstream/8886

Upstream sequence

TGCCTGGTAGGCAGAATAACTACCTTAATTTTTCAAGGTGATTAAGCTGATTAAGTAAGAACACTGTGATTCTTCATTCATTCGTCTTCACTTAACCAGA

Downstream sequence

ctcgtgatctgcctgcctcggccggccaaagtgctggcattacaggtgtgagccaccgcgcccggccTCTAATCCTTGATTTTGGAGGTCTCTGTTAAAA