VISDB Viral Integration Site DataBase

VIS ID

TVIS10009096

Fusion event

HBV-POC5 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

Polymerase|

Start

2510

Orient

-

Integrated sequence

CGCCGCGTCGCAGAAGATCTCAATCTCGGGAATCTCAATGTTAGTATTCCTTGGACTCATAAGGTGGGGAACTTTACTGGGCTTTATTCTTCTACTGTAC| |CTGTCTTTAATCCTCATTGGAAAACACCATCTTTTCCTAATATACATTTACACCAAGACATTATCAAAAAATGTGAACAGTTTGTAGGCCCACTCACAGT

Chromosome

chr5

Cytoband

q13.3

Reference genome

Start

End

74971395/75675570 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-2054 ; hsa-mir-6781-3p ; hsa-mir-2682-3p ; hsa-mir-643 ; hsa-mir-6877-3p ; hsa-mir-6819-3p ; hsa-mir-7109-3p

Nearest miRNA

hsa-mir-10397/Upstream/2796907; hsa-mir-103a-1/Downstream/7164585;

Nearest TSS

Nearest CpG islands

None/Target, chr5-CpG: 87/Upstream/63625, chr5-CpG: 41/Downstream/41567

Upstream sequence

ttctttcagaacagcaacaaagttgctaaaccagtgatcaggaaagagagagagcgaggacttccaacacaaaaagtataataaagaactattatgaata

Downstream sequence

TTTTTAAAGAAAAATAACTTCTTTTCTTAAAGTATCTTATAAAAACGTTTATTTGTACATAAACAACTGGATAACCATTATAAATAGGAGATACTCTTGC