Basic Information
VIS ID
TVIS10009113
Fusion event
HBV-chr10 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
X protein|
Start
1776
Orient
+
Integrated sequence
CAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACT| |AGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCA
Host Sequence
Chromosome
chr10
Cytoband
q22.3
Reference genome
End
78570486/76810728 (Hg38)
Orient
-
Location type
Intergenic
Fragile sites / regions
Nearest miRNA
hsa-mir-1265/Upstream/1258175; hsa-mir-107/Downstream/9453966;
Nearby gene
LRMDA(-253360) ; KCNMA1(+58873) ;
Upstream sequence
aGCACATTACAGAACAGCTTCTTTCCAGATTTTCCTAAACTACAGTTACAGTTAAGCTTATCAATGCTGAACTTCTTTTCCCAGTTACCTTGCTTTGCTG
Downstream sequence
CTACTCCCACAGTCTTTTGAGCTATCCAGCATTCGAAGGATCTGagatttgaactcaagaattgtttctgaccccctcactctactaggtgatcttaagc
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
Curate