VISDB Viral Integration Site DataBase

VIS ID

TVIS10009118

Fusion event

HBV-GPRC5A integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

X protein|precore/core protein|

Start

1835

Orient

+

Integrated sequence

GAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTG| |CCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCTTATAAAGAATTTGGAGCT

Chromosome

chr12

Cytoband

p13.1

Reference genome

Start

End

13063722/12910788 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-30a-5p ; hsa-mir-26b-5p ; hsa-mir-148a-3p ; hsa-mir-130a-3p ; hsa-mir-152-3p ; hsa-mir-301a-3p ; hsa-mir-130b-3p ; hsa-mir-148b-3p ; hsa-mir-454-3p ; hsa-mir-301b-3p ; hsa-mir-1914-3p ; hsa-mir-4295 ; hsa-mir-3666 ; hsa-mir-5194 ; hsa-mir-5197-3p ; hsa-mir-6738-5p ; hsa-mir-6782-5p ; hsa-mir-4696 ; hsa-mir-6746-5p ; hsa-mir-7847-3p ; hsa-mir-3165 ; hsa-mir-6880-5p ; hsa-mir-8071 ; hsa-mir-6862-5p ; hsa-mir-4253 ; hsa-mir-3622b-5p ; hsa-mir-6894-5p ; hsa-mir-765 ; hsa-mir-7154-3p ; hsa-mir-766-5p ; hsa-mir-4784 ; hsa-mir-3150b-3p ; hsa-mir-6810-5p ; hsa-mir-4652-5p ; hsa-mir-3191-3p ; hsa-mir-3144-5p ; hsa-mir-631 ; hsa-mir-3661 ; hsa-mir-338-3p ; hsa-mir-4530 ; hsa-mir-5586-5p ; hsa-mir-8485 ; hsa-mir-107 ; hsa-mir-103a-3p ; hsa-mir-6838-5p ; hsa-mir-497-5p ; hsa-mir-424-5p ; hsa-mir-195-5p ; hsa-mir-16-5p ; hsa-mir-15a-5p ; hsa-mir-15b-5p ; hsa-mir-3189-3p ; hsa-mir-212-5p ; hsa-mir-500b-5p ; hsa-mir-362-5p ; hsa-mir-30e-3p ; hsa-mir-30d-3p ; hsa-mir-30a-3p ; hsa-mir-3679-3p ; hsa-mir-222-5p ; hsa-mir-4669 ; hsa-mir-3657 ; hsa-mir-3667-3p ; hsa-mir-6734-3p ; hsa-mir-511-3p ; hsa-mir-466 ; hsa-mir-3140-5p ; hsa-mir-4793-5p ; hsa-mir-1273g-5p ; hsa-mir-1304-5p ; hsa-mir-6765-5p ; hsa-mir-4722-5p ; hsa-mir-1827 ; hsa-mir-6857-3p ; hsa-mir-4649-3p ; hsa-mir-3664-3p ; hsa-mir-4433a-3p ; hsa-mir-4459 ; hsa-mir-4768-3p ; hsa-mir-940 ; hsa-mir-6893-5p ; hsa-mir-6808-5p ; hsa-mir-4499 ; hsa-mir-34b-3p ; hsa-mir-105-5p ; hsa-mir-1233-5p ; hsa-mir-1237-3p ; hsa-mir-1252-3p ; hsa-mir-1273h-5p ; hsa-mir-149-3p ; hsa-mir-194-3p ; hsa-mir-30b-3p ; hsa-mir-363-5p ; hsa-mir-3689a-3p ; hsa-mir-3689b-3p ; hsa-mir-3689c ; hsa-mir-372-5p ; hsa-mir-3942-3p ; hsa-mir-4257 ; hsa-mir-4468 ; hsa-mir-4519 ; hsa-mir-4534 ; hsa-mir-4728-5p ; hsa-mir-4779 ; hsa-mir-542-3p ; hsa-mir-6758-5p ; hsa-mir-6778-5p ; hsa-mir-6779-5p ; hsa-mir-6780a-5p ; hsa-mir-6785-5p ; hsa-mir-6799-5p ; hsa-mir-6802-5p ; hsa-mir-6815-5p ; hsa-mir-6847-5p ; hsa-mir-6856-5p ; hsa-mir-6865-5p ; hsa-mir-6883-5p ; hsa-mir-7106-5p ; hsa-mir-7158-5p ; hsa-mir-767-3p ; hsa-mir-7853-5p

Nearest miRNA

hsa-mir-1244-3/Upstream/146045; hsa-let-7i/Downstream/5041;

Nearest TSS

Nearest CpG islands

None/Target, chr12-CpG: 104/Upstream/19055, chr12-CpG: 170/Downstream/89097

Nearest cancer related gene

GPRC5A(TSG, No orient, 0)

Upstream sequence

GCATTCCCCAGTTTCCCCTGGTAATCACTCCACCCTGTGCATCTGTAGGACTTTGAAATGCTCTTATCAGGGTCTGTCTCATTGCACTGTTATTTATGTA

Downstream sequence

CCTGTCATATGTTCCTTACTCTCCAGTGTCAGCTGCAAGGAGGGATCATTCTGGTTAATCTTTATGTGCTTCACCATCTCTCTCtttttttttttttttt