VISDB Viral Integration Site DataBase

VIS ID

TVIS10009125

Fusion event

HBV-UGGT2 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

X protein|precore/core protein|

Start

1814

Orient

+

Integrated sequence

GACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCAC| |CATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGAC

Chromosome

chr13

Cytoband

q32.1

Reference genome

Start

End

96511325/95859071 (Hg38)

Orient

+

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-1-3p ; hsa-mir-218-5p ; hsa-mir-1247-3p ; hsa-mir-1976 ; hsa-mir-3155a ; hsa-mir-3155b ; hsa-mir-3653-5p ; hsa-mir-4279 ; hsa-mir-4532 ; hsa-mir-4722-3p ; hsa-mir-484 ; hsa-mir-5571-5p ; hsa-mir-6715b-3p ; hsa-mir-6727-3p ; hsa-mir-6747-3p ; hsa-mir-6752-3p ; hsa-mir-6778-3p ; hsa-mir-6791-3p ; hsa-mir-6829-3p ; hsa-mir-6836-3p

Nearest miRNA

hsa-mir-1297/Upstream/3368851; hsa-mir-1267/Downstream/568158;

Nearest TSS

Nearest CpG islands

None/Target, chr13-CpG: 551/Upstream/181379, chr13-CpG: 81/Downstream/193904

Upstream sequence

TGAGACACCAAATTGCTGCGGAGACACTAAATTTCACGGAATTTGATTATGCTGTAGGGAGAATAGGAAGAAACAGAGTATACTTTGTAGCAGGAGTATA

Downstream sequence

GGGCTGAGTAAAGGGTAATAGCTGTTGATCACCTGAAATCTTCTAAATATAAAATGCCTCAGATCATGGTGCCCAGCAATCAATACACTACACAGACGAA