Basic Information
VIS ID
TVIS10009132
Fusion event
HBV-CTXND1 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
30271481
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Region type
X protein|
Start
1809
Orient
-
Integrated sequence
TCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACC| |AGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACA
Host Sequence
Chromosome
chr15
Cytoband
q25.1
Reference genome
GRCh37/hg19
Start
80498203/80205861 (Hg38)
End
80498203/80205861 (Hg38)
Orient
-
Location type
Intronic
Target gene
CTXND1
Nearest miRNA
hsa-mir-10393/Upstream/995990; hsa-mir-11181/Downstream/375242;
Nearest TSS
ENST00000557528/Upstream/28454; ENST00000529181/Downstream/46352;
Nearest CpG islands
None/Target, chr15-CpG: 55/Upstream/52695, chr15-CpG: 86/Downstream/45811
Nearby gene
FAH(-19279) ; LINC00927(+57207) ;
Upstream sequence
tcagttgaggcgatggatttgagacttctctctcattctcccagttgacatcatgagaataaaaagcctttttccctggaaatactcattgtttcagtta
Downstream sequence
ctggctttctgtacagtgagcaacaggacccagaccaaacccctggtgtttcagtcacacaatcttgaaaatcaagttatcctttatttttgccaatttg
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
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