Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10009137
Fusion event
HBV-C16orf52 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
X protein|
Start
1805
Orient
+
Integrated sequence
TACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCG| |CACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATG
Host Sequence
Chromosome
chr16
Cytoband
p12.2
Reference genome
Start
End
22051649/22040328 (Hg38)
Orient
+
Location type
Intronic
Target gene
Nearest miRNA
hsa-mir-1225/Upstream/534193; hsa-mir-11401/Downstream/2162788;
Nearest CpG islands
None/Target, chr16-CpG: 29/Upstream/31592, chr16-CpG: 28/Downstream/122029
Upstream sequence
gacacataagaggggaacaacacacactagggcctatccgagggtggaagaagggagaggatcaggaaaaaataactaataggtactaggcttaatacct
Downstream sequence
ggatgatgaaatgatctgtacaaccaacccccataacacaagtttacctatgtaacctgcacatgtacccctgaacttaaaagtattttaaaaattacaa
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.