VISDB Viral Integration Site DataBase

VIS ID

TVIS10009140

Fusion event

HBV-RBFOX1 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

X protein|precore/core protein|

Start

1827

Orient

-

Integrated sequence

AAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTT| |CACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCTTATAAAGAAT

Chromosome

chr16

Cytoband

p13.3

Reference genome

Start

End

6973091/6923090 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-30a-5p ; hsa-let-7b-5p ; hsa-mir-3157-5p ; hsa-mir-153-5p ; hsa-mir-935 ; hsa-mir-4691-3p ; hsa-mir-1305 ; hsa-mir-6809-3p ; hsa-mir-6833-3p ; hsa-mir-4768-5p ; hsa-mir-498 ; hsa-mir-4753-3p ; hsa-mir-627-3p ; hsa-mir-6832-3p ; hsa-mir-562

Nearest miRNA

hsa-mir-1225/Upstream/1290524; hsa-mir-11401/Downstream/4383350;

Nearest TSS

Nearest CpG islands

None/Target, chr16-CpG: 29/Upstream/439108, chr16-CpG: 23/Downstream/381242

Upstream sequence

AACTACTTATAAATCTATAGGCAGTGTATAAGCAAACCATAGACAGTGCAGTACCGTCGGCTGTTTATACAAGAGCTGTTATTACCCCTAAGCCCAGAAG

Downstream sequence

GCAATGAGAGAAAGTGATTTGTAGAATTCCAAAGGAGATAGGAAAGCAGCTGGTCCAGTGTGAGTCTgagaataaataccctggtccctgctcctggtct