Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10009146
Fusion event
HBV-GRB14 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
X protein|precore/core protein|
Start
1821
Orient
-
Integrated sequence
TGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAA| |CTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCTTATA
Host Sequence
Chromosome
chr2
Cytoband
q24.3
Reference genome
End
165466959/164610449 (Hg38)
Orient
-
Location type
Intronic
Target gene
miRNAs that regulate target gene
Nearest miRNA
hsa-mir-128-1/Upstream/4202567; hsa-mir-10b/Downstream/3972494;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/873448, chr2-CpG: 87/Downstream/10603
Upstream sequence
CAGTTCACTGGGCACTCACTTATAATTATACTATATAaaaaataatgtataaaatcagaaatatcttgattacacggatcaaattttcatacgtgttaaa
Downstream sequence
tgaaagcaaaagatacgtacttttaaaatccacttagtccaggatctagattcaattttatttttGCATTACAAAGAAATAATTGTCAAGaaaaaatttt
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.