Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10009149
Fusion event
HBV-DNAJB3 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
X protein|
Start
1790
Orient
+
Integrated sequence
ACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGC| |ATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGG
Host Sequence
Chromosome
chr2
Cytoband
q37.1
Reference genome
End
234651965/233743319 (Hg38)
Orient
-
Location type
UTR3
Target gene
Nearest miRNA
hsa-mir-10b/Upstream/1192746; hsa-mir-149/Downstream/3767612;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/176339, chr2-CpG: 42/Downstream/281
Upstream sequence
TGCTATTTATTATGAAGGACTTTAACTCAACTCTCCATCTTCCTCCACTTCCACCCTTTCTTGGCCATTCTCAATGATTCTCTTGGTGGTGATTTTTTTA
Downstream sequence
CCATCAACTATTTCAGTGGAAGTCGACATGGACTTGAAGCTGCCTGTCCCATCACTACCGTAGGACATGCAGAAGGAAGAAAGGCCCCCACTTCCCAGGG
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.