Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10009157
Fusion event
HBV-DSCAM integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
precore/core protein|
Start
1897
Orient
+
Integrated sequence
GGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTT| |GGGGCATGGACATCGACCCTTATAAAGAATTTGGAGCTACTGTGGAGTTACTCTCGTTTTTGCCTTCTGACTTCTTTCCTTCAGTACGAGATCTTCTAGA
Host Sequence
Chromosome
chr21
Cytoband
q22.2
Reference genome
Start
End
42136262/40764336 (Hg38)
Orient
+
Location type
Intronic
Target gene
Nearest miRNA
hsa-let-7c/Upstream/551905; hsa-mir-3197/Downstream/403221;
Nearest CpG islands
None/Target, chr21-CpG: 261/Upstream/581304, chr21-CpG: 34/Downstream/77248
Upstream sequence
caaatttacaagaaaaaaacaaacaactccatcaaaaagtgggtcaagtatattagcagacacttctcaaaagaagatatttatgccgccaaaaaaaaaa
Downstream sequence
aaaaatgaaaaaaagctcatcatcactggtcattagagaaatgcaaatcaaaatcacaatgagataccatctcaagccagttagaatggtgatcattaag
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.