Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10009158
Fusion event
HBV-DSCAM integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
X protein|precore/core protein|
Start
1816
Orient
-
Integrated sequence
CTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCA| |TGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCC
Host Sequence
Chromosome
chr21
Cytoband
q22.2
Reference genome
Start
End
42136299/40764373 (Hg38)
Orient
-
Location type
Intronic
Target gene
Nearest miRNA
hsa-let-7c/Upstream/551942; hsa-mir-3197/Downstream/403184;
Nearest CpG islands
None/Target, chr21-CpG: 261/Upstream/581341, chr21-CpG: 34/Downstream/77211
Upstream sequence
agtgggtcaagtatattagcagacacttctcaaaagaagatatttatgccgccaaaaaaaaaaaaaaatgaaaaaaagctcatcatcactggtcattaga
Downstream sequence
gaaatgcaaatcaaaatcacaatgagataccatctcaagccagttagaatggtgatcattaagaagtctggaaacaacagacgctggtgaggatgcagag
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.