VISDB Viral Integration Site DataBase

VIS ID

TVIS10009159

Fusion event

HBV-SYNGR1 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

X protein|

Start

1780

Orient

-

Integrated sequence

AATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGA| |GGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCT

Chromosome

chr22

Cytoband

q13.1

Reference genome

Start

End

39775262/39379257 (Hg38)

Orient

-

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-215-5p ; hsa-mir-192-5p ; hsa-mir-1301-3p ; hsa-mir-4727-5p ; hsa-mir-6727-5p ; hsa-mir-1228-5p ; hsa-mir-6763-5p ; hsa-mir-3150a-3p ; hsa-mir-6816-5p ; hsa-mir-3196 ; hsa-mir-3180-3p ; hsa-mir-3180 ; hsa-mir-486-3p ; hsa-mir-6825-5p ; hsa-mir-939-5p ; hsa-mir-1343-5p ; hsa-mir-3175 ; hsa-mir-6883-5p ; hsa-mir-4728-5p ; hsa-mir-6785-5p ; hsa-mir-149-3p ; hsa-mir-6787-5p ; hsa-mir-663a ; hsa-mir-1908-5p ; hsa-mir-423-5p ; hsa-mir-3184-5p ; hsa-mir-4314 ; hsa-mir-6821-3p ; hsa-mir-6790-3p ; hsa-mir-378g ; hsa-mir-4486 ; hsa-mir-6860 ; hsa-mir-612 ; hsa-mir-3187-5p ; hsa-mir-5189-5p ; hsa-mir-1285-3p ; hsa-mir-6800-3p ; hsa-mir-6738-3p ; hsa-mir-544a ; hsa-mir-192-3p ; hsa-mir-5001-3p ; hsa-mir-197-3p ; hsa-mir-6879-3p ; hsa-mir-6817-5p ; hsa-mir-4769-3p ; hsa-mir-6872-3p ; hsa-mir-513b-3p ; hsa-mir-6881-3p ; hsa-mir-6749-3p ; hsa-mir-6792-3p ; hsa-mir-4691-5p ; hsa-mir-211-5p ; hsa-mir-204-5p ; hsa-mir-617 ; hsa-mir-3117-3p ; hsa-mir-3124-3p ; hsa-mir-130b-5p ; hsa-mir-877-3p ; hsa-mir-660-3p ; hsa-mir-5193 ; hsa-mir-6865-3p ; hsa-mir-8083 ; hsa-mir-4759 ; hsa-mir-3169

Nearest miRNA

hsa-mir-1286/Upstream/1390404; hsa-let-7a-3/Downstream/1434626;

Nearest TSS

Nearest CpG islands

None/Target, chr22-CpG: 279/Upstream/4705, chr22-CpG: 18/Downstream/2403

Upstream sequence

AGCCCCCAGCAGCCAGGACCTCATGCTAACATAGTGGGAAACCCCAGAGGGCTACACCTTATCCCTTAGCCCAATTTCTTTAGACCTAGTCTGCCTTTCC

Downstream sequence

CAAGGTGCTGGCACTTTGCTTTAAATACCCACCTCCCAGAAAGTGCTTCCCCTCAGAACTTTGGTCAATGAGTACAATCAAAAGGTAATGCCCTAgctgg