Basic Information
VIS ID
TVIS10009175
Fusion event
HBV-LOC101927145 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
30271481
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Region type
X protein|
Start
1793
Orient
-
Integrated sequence
GACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATA| |AATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGG
Host Sequence
Chromosome
chr4
Cytoband
q13.1
Reference genome
GRCh37/hg19
Start
63083389/62217671 (Hg38)
End
63083389/62217671 (Hg38)
Orient
-
Location type
Intronic
Target gene
LOC101927145
Nearest miRNA
hsa-mir-12113/Upstream/1294987; hsa-mir-1243/Downstream/4059153;
Nearest TSS
ENST00000502981/Upstream/52117; ENST00000507857/Downstream/910640;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/1014588, chr4-CpG: 60/Downstream/1131458
Nearby gene
LPHN3(-145221) ;
Upstream sequence
ttccattccacttgtgttgattccattccgttcctttcgattgcattccattccattgcattccattccattccattccattccgttccattccattcgt
Downstream sequence
gtcttaactaagtaaaattgtaattcttattggtgttcaaactttcccagctttggatagtgtgagtttctctcagctggctcctgagtcctttttatga
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
Curate