VISDB Viral Integration Site DataBase

VIS ID

TVIS10009178

Fusion event

HBV-BMPR1B integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

precore/core protein|Core and e antigen|

Start

2060

Orient

+

Integrated sequence

CTTCTGACTTCTTTCCTTCAGTACGAGATCTTCTAGATACCGCCTCAGCTCTGTATCGGGAAGCCTTAGAGTCTCCTGAGCATTGTTCACCTCACCATAC| |TGCACTCAGGCAAGCAATTCTTTGCTGGGGGGAACTAATGACTCTAGCTACCTGGGTGGGTGTTAATTTGGAAGATCCAGCGTCTAGAGACCTAGTAGTC

Chromosome

chr4

Cytoband

q22.3

Reference genome

Start

End

96072951/95151800 (Hg38)

Orient

-

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-125b-5p ; hsa-let-7a-5p ; hsa-mir-22-3p ; hsa-mir-6792-3p ; hsa-mir-4691-5p ; hsa-mir-4705 ; hsa-mir-4668-3p ; hsa-mir-548c-3p

Nearest miRNA

hsa-mir-12113/Upstream/7851217; hsa-mir-1243/Downstream/3845587;

Nearest TSS

Nearest CpG islands

None/Target, chr4-CpG: 46/Upstream/393142, chr4-CpG: 20/Downstream/396505

Upstream sequence

ttccacttgggttgattccattccgttcctttcgattgcattccattccattgcattccattccattccattccattccattccgttccattccattcgt

Downstream sequence

GGGGTGCTCCCAAAAGATTGTTCAGAGCAGCAGCCTCTAATGTAATTATTATAAGGAGTTAATCTTAAGAAGGTGAAAAAGAAGATACTAGAAGCCTGCA