VISDB Viral Integration Site DataBase

VIS ID

TVIS10009188

Fusion event

HBV-NUS1 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

S protein|Polymerase|large S protein|middle S protein|

Start

455

Orient

+

Integrated sequence

CAACTTGTCCTGGTTATCGCTGGATGTGTCTGCGGCGTTTTATCATCTTCCTCTTCATCCTGCTGCTATGCCTCATCTTCTTGTTGGTTCTTCTGGACTA| |TCAAGGTATGTTGCCCGTTTGTCCTCTAATTCCAGGATCCTCAACAACCAGCACGGGACCATGCCGGACCTGCATGACTACTGCTCAAGGAACCTCTATG

Chromosome

chr6

Cytoband

q22.1

Reference genome

Start

End

118030307/117709144 (Hg38)

Orient

+

Location type

UTR3

Target gene

miRNAs that regulate target gene

hsa-mir-375 ; hsa-mir-32-5p ; hsa-mir-877-3p ; hsa-mir-31-3p ; hsa-mir-484 ; hsa-mir-197-3p ; hsa-mir-29b-3p ; hsa-mir-19a-3p ; hsa-mir-19b-3p ; hsa-mir-130a-3p ; hsa-mir-301a-3p ; hsa-mir-130b-3p ; hsa-mir-518a-5p ; hsa-mir-527 ; hsa-mir-454-3p ; hsa-mir-301b-3p ; hsa-mir-4295 ; hsa-mir-3666 ; hsa-mir-27a-3p ; hsa-mir-105-5p ; hsa-mir-27b-3p ; hsa-mir-144-3p ; hsa-mir-369-3p ; hsa-mir-374a-5p ; hsa-mir-651-3p ; hsa-mir-374b-5p ; hsa-mir-5692c ; hsa-mir-5692b ; hsa-mir-7853-5p ; hsa-mir-548t-5p ; hsa-mir-3609 ; hsa-mir-548ah-5p ; hsa-mir-548az-5p ; hsa-mir-2115-3p ; hsa-mir-490-3p ; hsa-mir-552-5p ; hsa-mir-580-3p ; hsa-mir-1277-5p ; hsa-mir-4490 ; hsa-mir-33a-3p ; hsa-mir-216a-3p ; hsa-mir-128-3p ; hsa-mir-3681-3p ; hsa-mir-1283 ; hsa-mir-195-3p ; hsa-mir-16-2-3p ; hsa-mir-34b-3p ; hsa-mir-6827-5p ; hsa-mir-504-3p ; hsa-mir-3682-3p ; hsa-mir-4705 ; hsa-mir-205-3p ; hsa-mir-649 ; hsa-mir-548n ; hsa-mir-107 ; hsa-mir-641 ; hsa-mir-103a-3p ; hsa-mir-3617-5p ; hsa-mir-514b-5p ; hsa-mir-513c-5p ; hsa-mir-6794-3p ; hsa-mir-4465 ; hsa-mir-26b-5p ; hsa-mir-26a-5p ; hsa-mir-1297 ; hsa-mir-4639-3p ; hsa-mir-5697 ; hsa-mir-3680-5p ; hsa-mir-603 ; hsa-mir-8485 ; hsa-mir-8064

Nearest miRNA

hsa-mir-10398/Upstream/10924924; hsa-mir-1202/Downstream/1359903;

Nearest TSS

Nearest CpG islands

None/Target, chr6-CpG: 120/Upstream/32932, chr6-CpG: 166/Downstream/197735

Upstream sequence

gcactttgggaggccgaggcgggcggatcacaaggtcaggagatcgagaccatcttggctaacacggtgaaaccccgtctttactaaaaatacaaaaaat

Downstream sequence

AACTTGAATGGCATTGGTTGTTCTGTAATTCCTGCCAAAAGCATCACAAGTTGTACATCATCAAGGCTCCCTTTGCACTCCCAAGAAGAACTGGTAATTT