VISDB Viral Integration Site DataBase

VIS ID

TVIS10009203

Fusion event

HBV-ASAP1 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

precore/core protein|Core and e antigen|

Start

1990

Orient

-

Integrated sequence

TGGCTTTGGGGCATGGACATCGACCCTTATAAAGAATTTGGAGCTACTGTGGAGTTACTCTCGTTTTTGCCTTCTGACTTCTTTCCTTCAGTACGAGATC| |TTCTAGATACCGCCTCAGCTCTGTATCGGGAAGCCTTAGAGTCTCCTGAGCATTGTTCACCTCACCATACTGCACTCAGGCAAGCAATTCTTTGCTGGGG

Chromosome

chr8

Cytoband

q24.21

Reference genome

Start

End

131396549/130384303 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-98-5p ; hsa-mir-32-5p ; hsa-mir-106b-5p ; hsa-mir-203a-3p ; hsa-mir-136-5p ; hsa-mir-544a ; hsa-mir-136-3p ; hsa-mir-432-5p ; hsa-mir-493-3p ; hsa-mir-208a-3p ; hsa-mir-208b-3p ; hsa-mir-27b-5p ; hsa-mir-3138 ; hsa-mir-3148 ; hsa-mir-4432 ; hsa-mir-4463 ; hsa-mir-4520-3p ; hsa-mir-4635 ; hsa-mir-4720-3p ; hsa-mir-499a-5p ; hsa-mir-6124 ; hsa-mir-6864-5p ; hsa-mir-8071 ; hsa-mir-8087 ; hsa-mir-875-3p

Nearest miRNA

hsa-mir-1204/Upstream/375850; hsa-mir-10400/Downstream/2662178;

Nearest TSS

Nearest CpG islands

None/Target, chr8-CpG: 109/Upstream/25232, chr8-CpG: 141/Downstream/58699

Upstream sequence

gtggctcacgcctgtaatcccagcactttgggaggccgaggtgggcagatcacaaggtcaggagatcgagaccatcttggctaacacggtgaaaccccgt

Downstream sequence

TTCAGATGCAACATCAAAGCTGTCATTGCTATGTAATTTACAGCCTGGTCTGCATACAAGCATCCATTCTGTGTTAGTATGTGCCACCCTCCCCCTCTTC