VISDB Viral Integration Site DataBase

VIS ID

TVIS10009204

Fusion event

HBV-NRG1 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

X protein|

Start

1761

Orient

-

Integrated sequence

GGACTCTTGGACTCTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTT| |AAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTA

Chromosome

chr8

Cytoband

p12

Reference genome

Start

End

31558821/31701305 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-124-3p ; hsa-mir-125a-3p

Nearest miRNA

hsa-mir-124-1/Upstream/1743957; hsa-mir-10400/Downstream/9569743;

Nearest TSS

Nearest CpG islands

None/Target, chr8-CpG: 109/Upstream/60475, chr8-CpG: 169/Downstream/846584

Upstream sequence

tccagtcttcttgagtgatatctctggatgtgggagtgaaccaaatgaatagcgcctgaagcgaacccctagcaaaccacagcagccctacagaggaggg

Downstream sequence

GTGCCACTGTGTGAACATTTCTCACTCTTGTGAGCATGTTTCTAAATCCCAAATCAATCTGACAAAGGATTTTCTGTGAATTTCTTGTTAATTTCTTGAC