VISDB Viral Integration Site DataBase

VIS ID

TVIS10009243

Fusion event

HBV-TCP11L1 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

S protein|Polymerase|large S protein|middle S protein|

Start

354

Orient

-

Integrated sequence

CTCGTGGTGGACTTCTCTCAATTTTCTAGGGGGAACTACCGTGTGTCTTGGCCAAAATTCGCAGTCCCCAACCTCCAATCACTCACCAACCTCTTGTCCT| |CCAACTTGTCCTGGTTATCGCTGGATGTGTCTGCGGCGTTTTATCATCTTCCTCTTCATCCTGCTGCTATGCCTCATCTTCTTGTTGGTTCTTCTGGACT

Chromosome

chr11

Cytoband

p13

Reference genome

Start

End

33092890/33071344 (Hg38)

Orient

-

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-92b-3p ; hsa-mir-3124-3p ; hsa-mir-8087 ; hsa-mir-7161-5p ; hsa-mir-548u

Nearest miRNA

hsa-mir-210/Upstream/4593796; hsa-let-7a-2/Downstream/1870493;

Nearest TSS

Nearest CpG islands

None/Target, chr11-CpG: 30/Upstream/31044, chr11-CpG: 24/Downstream/90097

Upstream sequence

gcggaggtgtagtgagctgagattgtgccactgcactgcagcctgggcgacagagtgaaactgtgtctcgagaaaaaaaaaGAGTAAGGGTGTTAGGCCC

Downstream sequence

TGTCCTGTCAGCAGTTTCTGTCTGTGTTGTGAGGCTCAGGAGGGTATAAGTTATTTGCACCTGAGAGGATTCCCCAGGCAGGAGGCAAGGCATGTAGTTT