VISDB Viral Integration Site DataBase

VIS ID

TVIS10009268

Fusion event

HBV-SSBP2 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

X protein|precore/core protein|

Start

1821

Orient

+

Integrated sequence

TGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAA| |CTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCTTATA

Chromosome

chr5

Cytoband

q14.1

Reference genome

Start

End

80886413/81590594 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-4666b ; hsa-mir-5011-3p ; hsa-mir-6799-5p ; hsa-mir-6851-5p ; hsa-mir-3689d ; hsa-mir-6797-3p ; hsa-mir-6076 ; hsa-mir-4722-5p ; hsa-mir-7854-3p ; hsa-mir-1827 ; hsa-mir-219b-3p ; hsa-mir-4649-3p ; hsa-mir-1247-3p ; hsa-mir-4768-3p ; hsa-mir-940 ; hsa-mir-6893-5p ; hsa-mir-6808-5p ; hsa-mir-6516-5p ; hsa-mir-455-3p ; hsa-mir-6499-3p ; hsa-mir-4537 ; hsa-mir-493-3p ; hsa-mir-6779-5p ; hsa-mir-6780a-5p ; hsa-mir-3689c ; hsa-mir-3689b-3p ; hsa-mir-3689a-3p ; hsa-mir-30b-3p ; hsa-mir-1273h-5p ; hsa-mir-6883-5p ; hsa-mir-6785-5p ; hsa-mir-4728-5p ; hsa-mir-149-3p ; hsa-mir-7106-5p ; hsa-mir-25-5p ; hsa-mir-449b-5p ; hsa-mir-449a ; hsa-mir-34c-5p ; hsa-mir-34a-5p ; hsa-mir-139-3p ; hsa-mir-6087 ; hsa-mir-5091 ; hsa-mir-3192-5p ; hsa-mir-3149 ; hsa-mir-411-5p ; hsa-mir-4775 ; hsa-mir-6832-5p ; hsa-mir-1273f ; hsa-mir-664a-5p ; hsa-mir-4794 ; hsa-mir-4735-5p ; hsa-mir-7851-3p ; hsa-mir-619-3p ; hsa-mir-590-3p ; hsa-mir-4443 ; hsa-mir-1299 ; hsa-mir-3191-5p ; hsa-mir-650 ; hsa-mir-3612 ; hsa-mir-7160-5p ; hsa-mir-6884-5p ; hsa-mir-485-5p ; hsa-mir-6128 ; hsa-mir-875-3p ; hsa-mir-6824-3p ; hsa-mir-6764-3p ; hsa-mir-330-5p ; hsa-mir-326 ; hsa-mir-518c-5p ; hsa-mir-4478 ; hsa-mir-4419b ; hsa-mir-3929 ; hsa-mir-216b-5p ; hsa-mir-629-3p ; hsa-mir-6867-3p ; hsa-mir-4713-5p ; hsa-mir-6783-3p ; hsa-mir-1343-3p ; hsa-mir-4465 ; hsa-mir-26b-5p ; hsa-mir-26a-5p ; hsa-mir-1297 ; hsa-mir-23b-5p ; hsa-mir-23a-5p ; hsa-mir-6829-3p ; hsa-mir-6791-3p ; hsa-mir-4772-3p ; hsa-mir-1281 ; hsa-mir-6742-3p ; hsa-mir-6852-5p ; hsa-mir-939-3p ; hsa-mir-660-3p ; hsa-mir-4485-5p ; hsa-mir-7108-3p ; hsa-mir-4258 ; hsa-mir-6513-3p ; hsa-mir-8062 ; hsa-mir-3165 ; hsa-mir-363-5p ; hsa-mir-3656 ; hsa-mir-4433a-3p ; hsa-mir-4459 ; hsa-mir-4683 ; hsa-mir-6745 ; hsa-mir-6888-5p ; hsa-mir-1227-3p ; hsa-mir-1262 ; hsa-mir-1273g-3p ; hsa-mir-4252 ; hsa-mir-451b ; hsa-mir-4696 ; hsa-mir-4701-3p ; hsa-mir-4793-3p ; hsa-mir-508-5p ; hsa-mir-542-3p ; hsa-mir-550b-2-5p ; hsa-mir-6501-3p ; hsa-mir-6512-3p ; hsa-mir-661 ; hsa-mir-6720-5p ; hsa-mir-6736-5p ; hsa-mir-6776-5p ; hsa-mir-6849-3p ; hsa-mir-766-3p ; hsa-mir-7703

Nearest miRNA

hsa-mir-10397/Upstream/8711931; hsa-mir-103a-1/Downstream/1249561;

Nearest TSS

Nearest CpG islands

None/Target, chr5-CpG: 87/Upstream/196185, chr5-CpG: 217/Downstream/159384

Nearest cancer related gene

SSBP2(TSG, No orient, 0)

Upstream sequence

ctaaccctaaccctaaccctaaccctaaccctaaccctaaccctaaccctaaccctaaccctaaccctaaccctaaccctaaccctaaccctaaccctaa

Downstream sequence

tcgtccattcacaggctgttttccacatacctcacaaggtgctcacaagaaaaactgttggacaacaagagactggagagcctccctcaTGGAGATGACA