VISDB Viral Integration Site DataBase

VIS ID

TVIS10009271

Fusion event

HBV-CRPPA integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

S protein|Polymerase|large S protein|middle S protein|

Start

707

Orient

+

Integrated sequence

CCATCCCATCATCCTGGGCTTTCGGAAAATTCCTATGGGAGTGGGCCTCAGCCCGTTTCTCCTGGCTCAGTTTACTAGTGCCATTTGTTCAGTGGTTCGT| |AGGGCTTTCCCCCACTGTTTGGCTTTCAGTTATATGGATGATGTGGTATTGGGGGCCAAGTCTGTACAGCATCTTGAGTCCCTTTTTACCGCTGTTACCA

Chromosome

chr7

Cytoband

p21.2

Reference genome

Start

End

16237791/16198166 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-5093 ; hsa-mir-570-3p ; hsa-mir-4511 ; hsa-mir-875-3p ; hsa-mir-548b-3p ; hsa-mir-548f-3p ; hsa-mir-548e-3p ; hsa-mir-548az-3p ; hsa-mir-548ar-3p ; hsa-mir-548a-3p ; hsa-mir-4666a-5p ; hsa-mir-5689 ; hsa-mir-4536-3p ; hsa-mir-1273h-5p ; hsa-mir-1288-5p ; hsa-mir-149-3p ; hsa-mir-1827 ; hsa-mir-1910-3p ; hsa-mir-30b-3p ; hsa-mir-30c-1-3p ; hsa-mir-30c-2-3p ; hsa-mir-3122 ; hsa-mir-338-3p ; hsa-mir-3614-5p ; hsa-mir-3689a-3p ; hsa-mir-3689b-3p ; hsa-mir-3689c ; hsa-mir-3913-5p ; hsa-mir-4310 ; hsa-mir-4433a-3p ; hsa-mir-4459 ; hsa-mir-450a-1-3p ; hsa-mir-4514 ; hsa-mir-4692 ; hsa-mir-4728-5p ; hsa-mir-4768-3p ; hsa-mir-6089 ; hsa-mir-6500-3p ; hsa-mir-6511a-5p ; hsa-mir-6513-5p ; hsa-mir-6779-5p ; hsa-mir-6780a-5p ; hsa-mir-6785-5p ; hsa-mir-6788-5p ; hsa-mir-6799-5p ; hsa-mir-6808-5p ; hsa-mir-6849-3p ; hsa-mir-6883-5p ; hsa-mir-6893-5p ; hsa-mir-7106-5p ; hsa-mir-7157-5p ; hsa-mir-7977 ; hsa-mir-887-5p ; hsa-mir-940 ; hsa-mir-122-5p ; hsa-mir-1267 ; hsa-mir-129-5p ; hsa-mir-3135b ; hsa-mir-3194-3p ; hsa-mir-3652 ; hsa-mir-3672 ; hsa-mir-367-5p ; hsa-mir-4294 ; hsa-mir-431-5p ; hsa-mir-4423-5p ; hsa-mir-4430 ; hsa-mir-504-3p ; hsa-mir-5691 ; hsa-mir-5698 ; hsa-mir-6501-5p ; hsa-mir-6805-3p ; hsa-mir-6864-3p ; hsa-mir-744-3p ; hsa-mir-8055 ; hsa-mir-924

Nearest miRNA

hsa-mir-339/Upstream/9131121; hsa-mir-10399/Downstream/1929054;

Nearest TSS

Nearest CpG islands

None/Target, chr7-CpG: 39/Upstream/2206578, chr7-CpG: 17/Downstream/201331

Upstream sequence

ctacatgtaagttattagttattattTTCATAATAGGGTATTATTCTTTTGATCGGGATAGGGAGAAGAAGCACCCGGAAGAACATGTAGAGATAATCTT

Downstream sequence

taaaagaggaaggaatgcctcttgcagttgagacaagaggaaggcatctgtctcctgcctgtccctgggcaatggaatgtctcggtataaaacccgattg