VISDB Viral Integration Site DataBase

VIS ID

TVIS10009296

Fusion event

HBV-TOMM40L integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

precore/core protein|

Start

1862

Orient

+

Integrated sequence

AAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTAC| |TGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCTTATAAAGAATTTGGAGCTACTGTGGAGTTACTCTCGTTTTTGCCT

Chromosome

chr1

Cytoband

q23.3

Reference genome

Start

End

161199858/161230068 (Hg38)

Orient

-

Location type

UTR3

Target gene

miRNAs that regulate target gene

hsa-mir-2909 ; hsa-mir-513a-5p ; hsa-mir-1296-5p ; hsa-mir-6508-3p ; hsa-mir-3681-3p ; hsa-mir-216a-3p ; hsa-mir-128-3p ; hsa-mir-330-3p ; hsa-mir-4512 ; hsa-mir-7160-3p ; hsa-mir-6895-5p ; hsa-mir-27b-3p ; hsa-mir-27a-3p ; hsa-let-7a-5p ; hsa-let-7b-5p ; hsa-let-7c-5p ; hsa-let-7d-5p ; hsa-let-7e-5p ; hsa-let-7f-5p ; hsa-let-7g-5p ; hsa-let-7i-5p ; hsa-mir-202-3p ; hsa-mir-3155a ; hsa-mir-3155b ; hsa-mir-3921 ; hsa-mir-4458 ; hsa-mir-4500 ; hsa-mir-4645-5p ; hsa-mir-4649-3p ; hsa-mir-4653-5p ; hsa-mir-4673 ; hsa-mir-4677-3p ; hsa-mir-4679 ; hsa-mir-484 ; hsa-mir-5586-5p ; hsa-mir-7162-3p ; hsa-mir-760 ; hsa-mir-8070 ; hsa-mir-98-5p ; hsa-mir-501-3p ; hsa-mir-502-3p

Nearest miRNA

hsa-mir-101-1/Upstream/2807; hsa-mir-1182/Downstream/927039;

Nearest TSS

Nearest CpG islands

None/Target, chr1-CpG: 111/Upstream/27602, chr1-CpG: 54/Downstream/28619

Upstream sequence

ATAAGGCAGTTGGGAGTCTTGTCTCTAGGCCCTGATCCCCTGAACTATTCCTCAGTGAAGCCAGGTCTGAACATTAGAGAAAATCATGCTCTGGTATGAC

Downstream sequence

AGACTATCAGAGGTTCCAAAGGTCCTCCAGGGGGCCTCGGTCTGACACTGTCTTCTCTCACCATGCTCAGTTTTTTCTGAACCCAGAGCTCTGAGAGCCG