VISDB Viral Integration Site DataBase

VIS ID

TVIS10009301

Fusion event

HBV-THRAP3 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

S protein|Polymerase|large S protein|middle S protein|

Start

741

Orient

-

Integrated sequence

ATGGGAGTGGGCCTCAGCCCGTTTCTCCTGGCTCAGTTTACTAGTGCCATTTGTTCAGTGGTTCGTAGGGCTTTCCCCCACTGTTTGGCTTTCAGTTATA| |TGGATGATGTGGTATTGGGGGCCAAGTCTGTACAGCATCTTGAGTCCCTTTTTACCGCTGTTACCAATTTTCTTTTGTCTTTGGGTATACATTTAAACCC

Chromosome

chr1

Cytoband

p34.3

Reference genome

Start

End

36757660/36292059 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-877-3p ; hsa-mir-877-5p ; hsa-mir-615-3p ; hsa-mir-326 ; hsa-mir-125a-5p ; hsa-mir-125b-5p ; hsa-mir-559 ; hsa-mir-548b-5p ; hsa-mir-548a-5p ; hsa-mir-548c-5p ; hsa-mir-548d-5p ; hsa-mir-548j-5p ; hsa-mir-548h-5p ; hsa-mir-548i ; hsa-mir-3153 ; hsa-mir-548w ; hsa-mir-548y ; hsa-mir-548o-5p ; hsa-mir-548ab ; hsa-mir-548ad-5p ; hsa-mir-548ae-5p ; hsa-mir-548ak ; hsa-mir-548am-5p ; hsa-mir-3973 ; hsa-mir-548ap-5p ; hsa-mir-548aq-5p ; hsa-mir-548ar-5p ; hsa-mir-548as-5p ; hsa-mir-548au-5p ; hsa-mir-548ay-5p ; hsa-mir-6733-5p ; hsa-mir-6739-5p ; hsa-mir-6783-5p ; hsa-mir-548bb-5p ; hsa-mir-203a-3p ; hsa-mir-6838-5p ; hsa-mir-497-5p ; hsa-mir-424-5p ; hsa-mir-195-5p ; hsa-mir-16-5p ; hsa-mir-15b-5p ; hsa-mir-15a-5p ; hsa-mir-548p ; hsa-mir-5680 ; hsa-mir-625-3p ; hsa-mir-3936

Nearest miRNA

hsa-mir-12136/Upstream/1622365; hsa-mir-101-1/Downstream/869504;

Nearest TSS

Nearest CpG islands

None/Target, chr1-CpG: 111/Upstream/67573, chr1-CpG: 110/Downstream/14170

Upstream sequence

AGTGATGGAGAAGCTGGGTTGGGCCAGTTGCAGGTTCCATCTGAATATAAACTCAAGCAAGAGTTGGTGCTGTGCTTCTGAGGAGAATAAGCTTCAAGTT

Downstream sequence

TCTCTGTCCTAAGACATGGGAGCTACAGTGGAAATCTAGTGCCCAATATGGGACCGTGTTTGAACCAGCCATTTTTCCTTCCTCTTCTCAGTATGTTTGT