VISDB Viral Integration Site DataBase

VIS ID

TVIS10009309

Fusion event

HBV-PLXDC2 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

Polymerase|

Start

2702

Orient

+

Integrated sequence

CTCACAGTTAATGAGAAAAGAAGATTGCAATTGATTATGCCTGCCAGGTTTTATCCAAAGGTTACCAAATATTTACCATTGGATAAGGGTATTAAACCTT| |ATTATCCAGAACATCTAGTTAATCATTACTTCCAAACTAGACACTATTTACACACTCTATGGAAGGCGGGTATATTATATAAGAGAGAAACAACACATAG

Chromosome

chr10

Cytoband

p12.31

Reference genome

Start

End

20321233/20032304 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-148b-3p ; hsa-mir-1-3p ; hsa-mir-181a-5p ; hsa-let-7b-5p ; hsa-mir-573 ; hsa-mir-3616-5p ; hsa-mir-3152-3p ; hsa-mir-4635 ; hsa-mir-4694-5p ; hsa-mir-574-5p ; hsa-mir-1277-5p ; hsa-mir-599 ; hsa-mir-3912-5p ; hsa-mir-3924 ; hsa-mir-190a-3p ; hsa-mir-6755-3p ; hsa-mir-6867-5p ; hsa-mir-223-5p ; hsa-mir-198 ; hsa-mir-193a-5p ; hsa-mir-1273f ; hsa-mir-1304-3p ; hsa-mir-4781-3p ; hsa-mir-5011-5p ; hsa-mir-3976 ; hsa-mir-4789-3p ; hsa-mir-8485 ; hsa-mir-302f ; hsa-mir-3675-3p ; hsa-mir-136-3p ; hsa-mir-5698 ; hsa-mir-744-3p ; hsa-mir-6805-3p ; hsa-mir-5691 ; hsa-mir-4423-5p ; hsa-mir-6501-5p ; hsa-mir-143-5p ; hsa-mir-4430 ; hsa-mir-3652 ; hsa-mir-3622b-5p ; hsa-mir-122-5p ; hsa-mir-504-3p ; hsa-mir-3135b ; hsa-mir-3194-3p ; hsa-mir-6499-3p ; hsa-mir-367-5p ; hsa-mir-1267 ; hsa-mir-103b ; hsa-mir-5693 ; hsa-mir-7705 ; hsa-mir-617 ; hsa-mir-3605-3p ; hsa-mir-8087 ; hsa-mir-6854-5p ; hsa-mir-6885-3p ; hsa-mir-147a ; hsa-mir-5010-3p ; hsa-mir-6818-5p

Nearest miRNA

hsa-mir-1265/Upstream/2187111; hsa-mir-107/Downstream/519666;

Nearest TSS

Nearest CpG islands

None/Target, chr10-CpG: 68/Upstream/214287, chr10-CpG: 149/Downstream/1140895

Upstream sequence

caattaaaacagactaagggaggattatttcagaggcatgaaacagcaggtgcaatgtatgatgttggagaatatggacatattcatgggacaacaagaa

Downstream sequence

aaccattgtggttggtgtggcatgtgagatgaggaaaatgaagttggagagatggttgtgtcaagcacagtgtgtggtaaggatattggattttattcta