Fusion event
HBV-R3HDM2 integration
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Region type
X protein|precore/core protein|
Integrated sequence
AAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTT| |CACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCTTATAAAGAAT
End
57807845/57414062 (Hg38)
miRNAs that regulate target gene
Nearest miRNA
hsa-mir-1228/Upstream/219486; hsa-let-7i/Downstream/98626;
Upstream sequence
agcctcctgagtagctgagattacaggcacacaccaccatacccagctaaatttttttgtatttttagtagagagcgggtttcatcatgttggtcaggct
Downstream sequence
ggtcttgaactcctgacctcaaatgatccacccacctcagcctcccagagtgctgggatcacaggcgtgagccaccttgcccagccCACTCTATCTTTTT
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.