Basic Information
VIS ID
TVIS10009328
Fusion event
HBV-chr12 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
Polymerase|
Start
2812
Orient
-
Integrated sequence
ACATCTAGTTAATCATTACTTCCAAACTAGACACTATTTACACACTCTATGGAAGGCGGGTATATTATATAAGAGAGAAACAACACATAGCGCCTCATTT| |TGTGGGTCACCATATTCTTGGGAACAAGATCTACAGCATGGGGCAGAATCTTTCCACCAGCAATCCTCTGGGATTCTTTCCCGACCACCAGTTGGATCCA
Host Sequence
Chromosome
chr12
Cytoband
q23.1
Reference genome
End
98174574/97780796 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-let-7i/Upstream/216885; hsa-mir-1178/Downstream/158260;
Nearby gene
MIR135A2(-216885) ; MIR4303(+214587) ;
Nearest cancer related gene
MIR135A2(TSG, -216885) ;
Upstream sequence
TTTACATATTCTAATATATGTTTTATTTATATAGATATATTATGATACTCTTACAGAGAATCTATCAAAACCTTTTCACAATACAAAAAATGATGCTAAT
Downstream sequence
TACTATCACGGGTTTCAATGAGTGCTTTATTTCATAATGCAAAGCATTAAGGTTTACAGTCTTTTGATAGAAAAAGGTGGAAAAATCCATGTTGGTAATT
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
Curate