Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10009331
Fusion event
HBV-POTEB integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
precore/core protein|
Start
1871
Orient
+
Integrated sequence
GTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGC| |CTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCTTATAAAGAATTTGGAGCTACTGTGGAGTTACTCTCGTTTTTGCCTTCTGACTTC
Host Sequence
Chromosome
chr15
Cytoband
q11.2
Reference genome
Start
End
22072311/21429456 (Hg38)
Orient
+
Location type
Intronic
Target gene
Nearest miRNA
hsa-mir-3118-2/Upstream/22997; hsa-mir-10393/Downstream/84503;
Nearest CpG islands
None/Target, chr15-CpG: 55/Upstream/45398, chr15-CpG: 141/Downstream/21921
Upstream sequence
CCCCTCTGACCCTTTATAACAAGCCCACCTCATATCTGCTAGAGAAAAGACCAACAACGGCCTGAAAGGATCTCTTACCATGAAGGTCTCAGCTAATTCT
Downstream sequence
TAGCTAAGATGTGGGTTCCACATTAGGTTCTGAATACAGGAGGAAGGGTCAATTTGCTCACTTTGTGTGCGGATAAAGTCAGGATGCCCAGCGGCCAGAG
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.