Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10009333
Fusion event
HBV-NOMO1 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
X protein|
Start
1800
Orient
-
Integrated sequence
AGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGT| |CTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGG
Host Sequence
Chromosome
chr16
Cytoband
p13.11
Reference genome
Start
End
14981238/14887381 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
Target gene
miRNAs that regulate target gene
Nearest miRNA
hsa-mir-1225/Upstream/578010; hsa-mir-11401/Downstream/14127;
Nearest CpG islands
None/Target, chr16-CpG: 29/Upstream/53197, chr16-CpG: 166/Downstream/23568
Upstream sequence
catcatcaaatctttcttttttttttttttgagacggagtctcgccttgtcgcccaggctggagtgcagtggcgcaatctgggctcactgcaagctccgc
Downstream sequence
ctcctgggttcacaccattctcctgcctcagcctccgaagtagctgggactacaggcgtgtgccaccacacccggctaattcttttttttttttattttt
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.