Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10009334
Fusion event
HBV-NOMO1 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
Polymerase|
Start
2553
Orient
+
Integrated sequence
GTATTCCTTGGACTCATAAGGTGGGGAACTTTACTGGGCTTTATTCTTCTACTGTACCTGTCTTTAATCCTCATTGGAAAACACCATCTTTTCCTAATAT| |ACATTTACACCAAGACATTATCAAAAAATGTGAACAGTTTGTAGGCCCACTCACAGTTAATGAGAAAAGAAGATTGCAATTGATTATGCCTGCCAGGTTT
Host Sequence
Chromosome
chr16
Cytoband
p13.11
Reference genome
Start
End
14981282/14887425 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
Target gene
miRNAs that regulate target gene
Nearest miRNA
hsa-mir-1225/Upstream/578054; hsa-mir-11401/Downstream/14083;
Nearest CpG islands
None/Target, chr16-CpG: 29/Upstream/53241, chr16-CpG: 166/Downstream/23524
Upstream sequence
ccttgtcgcccaggctggagtgcagtggcgcaatctgggctcactgcaagctccgcctcctgggttcacaccattctcctgcctcagcctccgaagtagc
Downstream sequence
tgggactacaggcgtgtgccaccacacccggctaattcttttttttttttatttttagtagagacggggtttcaccatgttagccaggatggtcttgatc
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.