VISDB Viral Integration Site DataBase

VIS ID

TVIS10009335

Fusion event

HBV-NOMO3 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

X protein|

Start

1800

Orient

-

Integrated sequence

AGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGT| |CTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGG

Chromosome

chr16

Cytoband

p13.11

Reference genome

Start

End

16379884/16286027 (Hg38)

Orient

+

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-877-3p ; hsa-mir-766-3p ; hsa-mir-615-3p ; hsa-mir-484 ; hsa-mir-362-5p ; hsa-mir-149-5p ; hsa-let-7b-5p

Nearest miRNA

hsa-mir-1225/Upstream/642655; hsa-mir-11401/Downstream/14132;

Nearest TSS

Nearest CpG islands

None/Target, chr16-CpG: 29/Upstream/53028, chr16-CpG: 168/Downstream/23577

Upstream sequence

tcatcaaatctttcttttttttttttttttgagacggagtctcgccttgtcgcccaggctggagtgcagtggcgcaatctgggctcactgcaagctccgc

Downstream sequence

ctcctgggttcacaccattctcctgcctcagcctccgaagtagctgggactacaggcgtgcgccaccacacccggctaatttttttttttgtgtattttt