Fusion event
HBV-chr18 integration
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Region type
Polymerase|large S protein|
Integrated sequence
ATTGGGACTTCAATCCCAACAAGGACACCTGGCCAGACGCCAACAAGGTAGGAGCTGGAGCATTCGGGCTGGGTTTCACCCCACCGCACGGAGGCCTTTT| |GGGGTGGAGCCCTCAGGCTCAGGGCATACTACAAACTTTGCCAGCAAATCCGCCTCCTGCCTCCACCAATCGCCAGTCAGGAAGGCAGCCTACCCCGCTG
End
56872699/59205467 (Hg38)
Nearest miRNA
hsa-mir-1-2/Upstream/754309; hsa-mir-5011/Downstream/7876117;
Upstream sequence
gcactttatgcaaacagtcaggccaaatatgaaagtaaagtctatttttcaaaccgctcagtcctatgatgatacgttttttaaacaaaaatgaggactg
Downstream sequence
gagagagagaaattatatttcaaaacttataatacatttgtcattaaattccaaactcactagttgtttttaatattttgcctacattttacactaaccc
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.