Basic Information
VIS ID
TVIS10009345
Fusion event
HBV-chr19 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
Polymerase|
Start
891
Orient
+
Integrated sequence
TTTACCGCTGTTACCAATTTTCTTTTGTCTTTGGGTATACATTTAAACCCTAACAAAACAAAGAGATGGGGTTACTCTCTAAATTTTATGGGTTATGTCA| |TTGGATGTTATGGGTCCTTGCCACAAGAACACATCATACAAAAAATCAAAGAATGTTTTAGAAAACTTCCTATTAACAGGCCTATTGATTGGAAAGTATG
Host Sequence
Chromosome
chr19
Cytoband
q13.11
Reference genome
End
34444241/33953336 (Hg38)
Orient
+
Location type
Intergenic
Fragile sites / regions
Nearest miRNA
hsa-mir-10395/Upstream/13553982; hsa-let-7e/Downstream/1169364;
Nearby gene
KCTD15(-137575) ; LSM14A(+219111) ;
Upstream sequence
ATTGCTCCAGAGGACATGGCCACAGCTGCTCCCTTGCAGGCTGGTGGGCTTGACCTCACTGAGAACTGGGAATGACCTCTGCGTCCTTCACATTCCAGCA
Downstream sequence
GCTTCCAGTGGAGCTTGGAAGGTATTTTCTTTTAGCATTGGAGACCAGTTCTTTAATGGATGGAAAAAAAAAAAAAGTCTTGTGAAGGGAAGACTTAGAT
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
Curate