Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10009363
Fusion event
HBV-LOC100130264 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
X protein|
Start
1796
Orient
-
Integrated sequence
CTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAAT| |TGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTT
Host Sequence
Chromosome
chr20
Cytoband
p11.23
Reference genome
Start
End
19254387/19273743 (Hg38)
Orient
+
Location type
ncRNA_intronic
Fragile sites / regions
Target gene
Nearest miRNA
hsa-mir-103a-2/Upstream/803052; hsa-mir-1-1/Downstream/6934443;
Nearest CpG islands
None/Target, chr20-CpG: 39/Upstream/60485, chr20-CpG: 127/Downstream/483652
Upstream sequence
TTCTGACTCTGGTCCAGCCCCAGGAGGTGCCAATGCTGCTCCTCCTCTGACTGGAAGACAGGGACTCCATCCAGAAGACAGAAGATCTCCAAGCCACAGG
Downstream sequence
AGGCCATAGGTTCTGTTTAAATCCTCTTCCATGAGCTGTCTCCACAGCCTGTCCAATGGGCAAGGGGATGCTGAGAACACCCCCTTGGGCTGGGTCAAGG
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.