VISDB Viral Integration Site DataBase

VIS ID

TVIS10009367

Fusion event

HBV-TANGO2 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

X protein|

Start

1788

Orient

-

Integrated sequence

CGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAG| |GCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTG

Chromosome

chr22

Cytoband

q11.21

Reference genome

Start

End

20036026/20048503 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-4459 ; hsa-mir-887-5p ; hsa-mir-6779-5p ; hsa-mir-6780a-5p ; hsa-mir-3689c ; hsa-mir-3689b-3p ; hsa-mir-3689a-3p ; hsa-mir-30b-3p ; hsa-mir-1273h-5p ; hsa-mir-6788-5p ; hsa-mir-30c-2-3p ; hsa-mir-30c-1-3p ; hsa-mir-1273e ; hsa-mir-203b-3p ; hsa-mir-7158-3p ; hsa-mir-486-3p ; hsa-mir-6799-5p ; hsa-mir-6883-5p ; hsa-mir-6785-5p ; hsa-mir-4728-5p ; hsa-mir-149-3p ; hsa-mir-7106-5p ; hsa-mir-25-5p ; hsa-mir-658 ; hsa-mir-6087 ; hsa-mir-4722-5p ; hsa-mir-4768-3p ; hsa-mir-219b-3p ; hsa-mir-302f ; hsa-mir-455-3p ; hsa-mir-519e-5p ; hsa-mir-6077 ; hsa-mir-515-5p ; hsa-mir-5695 ; hsa-mir-7-5p ; hsa-mir-519d-5p ; hsa-mir-7853-5p ; hsa-mir-454-5p ; hsa-mir-105-5p ; hsa-mir-548b-3p ; hsa-mir-652-5p ; hsa-mir-6736-5p ; hsa-mir-4701-3p ; hsa-mir-1262 ; hsa-mir-7703 ; hsa-mir-6720-5p ; hsa-mir-6512-3p ; hsa-mir-1227-3p ; hsa-mir-542-3p ; hsa-mir-661 ; hsa-mir-4696 ; hsa-mir-6776-5p ; hsa-mir-4793-3p ; hsa-mir-766-3p ; hsa-mir-372-5p ; hsa-mir-371a-5p ; hsa-mir-616-5p ; hsa-mir-373-5p ; hsa-mir-371b-5p ; hsa-mir-6742-3p ; hsa-mir-6827-3p ; hsa-mir-340-3p ; hsa-mir-6849-3p ; hsa-mir-1273g-3p ; hsa-mir-6501-3p ; hsa-mir-3613-3p ; hsa-mir-451b ; hsa-mir-508-5p ; hsa-mir-4432 ; hsa-mir-6513-5p ; hsa-mir-3913-5p ; hsa-mir-3122 ; hsa-mir-450a-1-3p ; hsa-mir-197-3p ; hsa-mir-3165 ; hsa-mir-4736 ; hsa-mir-3665 ; hsa-mir-6089 ; hsa-mir-1827 ; hsa-mir-940 ; hsa-mir-6893-5p ; hsa-mir-6808-5p

Nearest miRNA

hsa-mir-185/Upstream/15283; hsa-let-7a-3/Downstream/37243;

Nearest TSS

Nearest CpG islands

None/Target, chr22-CpG: 279/Upstream/26926, chr22-CpG: 126/Downstream/31380

Upstream sequence

gggtatgtccttgtagcagcatgagaatggactaataaatacaccattgtttcttgagttttatttatttatttattttttggttgttttatgcaggagg

Downstream sequence

gtaaatctggtccttgttgctTGGGCAATTTGGAAGTTttgttcttgttttaattattgatttgtaagagttatttacccattctggatatgagtccttt