Basic Information
VIS ID
TVIS10009376
Fusion event
HBV-chr5 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
X protein|Polymerase|
Start
1615
Orient
-
Integrated sequence
CGACCACGGGGCGCACCTCTCTTTACGCGGACTCCCCGTCTGTGCCTTCTCATCTGCCGGACCGTGTGCACTTCGCTTCACCTCTGCACGTCGCATGGAG| |ACCACCGTGAACGCCCACCAAATATTGCCCAAGGTCTTACATAAGAGGACTCTTGGACTCTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAG
Host Sequence
Chromosome
chr5
Cytoband
q23.2
Reference genome
End
125280963/125945270 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-mir-10397/Upstream/6790554; hsa-mir-103a-1/Downstream/3152418;
Nearby gene
ZNF608(-1200158) ; GRAMD2B(+414825) ;
Upstream sequence
taaccctaaccctaaccctaaccctaaccctaaccctaaccctaaccctaaccctaaccctaaccctaaccctaaccctaaccctaaccctaaccctaac
Downstream sequence
TTTTACAATCCAGTTTGCAGAGTATCATGTTTTAAAACTGTAATTACCTTCCTCAGGTGGCAAACTTAGTTAAGGTGGTTTCTTTGAACTTTAGAAGATA
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
Curate