CENPW _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10009384
Fusion event
HBV-CENPW integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
30271481
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Region type
S protein|Polymerase|large S protein|middle S protein|
Start
677
Orient
-
Integrated sequence
AACCTTCGGACGGAAATTGCACCTGTATTCCCATCCCATCATCCTGGGCTTTCGGAAAATTCCTATGGGAGTGGGCCTCAGCCCGTTTCTCCTGGCTCAG| |TTTACTAGTGCCATTTGTTCAGTGGTTCGTAGGGCTTTCCCCCACTGTTTGGCTTTCAGTTATATGGATGATGTGGTATTGGGGGCCAAGTCTGTACAGC
Host Sequence
Chromosome
chr6
Cytoband
q22.32
Reference genome
GRCh37/hg19
Start
126707684/126386538 (Hg38)
End
126707684/126386538 (Hg38)
Orient
+
Location type
Intronic
Target gene
CENPW
Nearest miRNA
hsa-mir-10398/Upstream/6371281; hsa-mir-1202/Downstream/98093;
Nearest TSS
ENST00000381078/Upstream/46364; ENST00000485757/Downstream/732066;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/46297, chr6-CpG: 30/Downstream/256965
Nearby gene
CENPW(-37930) ; RSPO3(+732364) ;
Nearest cancer related gene
CENPW(OG, No orient, 0)
Upstream sequence
aattacagattagtttgcattttctggaatttatacaagtcaaatcacacagtttatattcttttgtctggtttctttccttccacacaatgattttgaa
Downstream sequence
GCCTTCTGCCATTTTAATGGGTTTGTGTTTCACAGATTGGCACAGATTAGGGTTTATATCTTTAAAGAGATGAAATAGTTGTGCAGTGTACACTAGAGAA
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
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