VISDB Viral Integration Site DataBase

VIS ID

TVIS10009402

Fusion event

HBV-UBE2D3 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

precore/core protein|Core and e antigen|

Start

2055

Orient

+

Integrated sequence

TTTGCCTTCTGACTTCTTTCCTTCAGTACGAGATCTTCTAGATACCGCCTCAGCTCTGTATCGGGAAGCCTTAGAGTCTCCTGAGCATTGTTCACCTCAC| |CATACTGCACTCAGGCAAGCAATTCTTTGCTGGGGGGAACTAATGACTCTAGCTACCTGGGTGGGTGTTAATTTGGAAGATCCAGCGTCTAGAGACCTAG

Chromosome

chr4

Cytoband

q24

Reference genome

Start

End

103762601/102841444 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-155-5p ; hsa-mir-101-3p ; hsa-mir-98-5p ; hsa-let-7b-5p ; hsa-mir-877-3p ; hsa-mir-423-5p ; hsa-mir-218-5p ; hsa-mir-136-5p ; hsa-mir-6126 ; hsa-mir-6864-5p ; hsa-mir-920 ; hsa-mir-6726-5p ; hsa-mir-5591-5p ; hsa-mir-4300 ; hsa-mir-3934-3p ; hsa-mir-3670 ; hsa-mir-539-5p ; hsa-mir-493-3p ; hsa-mir-4635 ; hsa-mir-3664-3p ; hsa-mir-4433a-3p ; hsa-mir-4459 ; hsa-mir-4768-3p ; hsa-mir-4453 ; hsa-mir-4538 ; hsa-mir-6854-5p ; hsa-mir-5003-3p ; hsa-mir-6833-5p ; hsa-mir-7847-3p ; hsa-mir-3190-3p ; hsa-mir-6894-5p ; hsa-mir-765 ; hsa-mir-7154-3p ; hsa-mir-766-5p ; hsa-mir-1468-3p ; hsa-mir-548x-5p ; hsa-mir-548g-5p ; hsa-mir-548f-5p ; hsa-mir-548aj-5p ; hsa-mir-4795-5p ; hsa-mir-4657 ; hsa-mir-4491 ; hsa-mir-4519 ; hsa-mir-301b-3p ; hsa-mir-130b-3p ; hsa-mir-301a-3p ; hsa-mir-3666 ; hsa-mir-4295 ; hsa-mir-454-3p ; hsa-mir-130a-3p ; hsa-mir-19b-3p ; hsa-mir-19a-3p ; hsa-mir-152-3p ; hsa-mir-148b-3p ; hsa-mir-148a-3p ; hsa-mir-188-3p ; hsa-mir-195-3p ; hsa-mir-4733-5p ; hsa-mir-16-2-3p ; hsa-mir-577 ; hsa-mir-888-5p ; hsa-mir-376c-3p ; hsa-mir-421 ; hsa-mir-7159-5p ; hsa-mir-676-5p ; hsa-mir-505-3p ; hsa-mir-6864-3p ; hsa-mir-3672 ; hsa-mir-769-5p ; hsa-mir-4786-5p ; hsa-mir-664a-5p ; hsa-mir-4794 ; hsa-mir-7162-3p ; hsa-mir-544b ; hsa-mir-6849-3p ; hsa-mir-6771-3p ; hsa-mir-1245b-3p ; hsa-mir-1249-5p ; hsa-mir-1257 ; hsa-mir-1321 ; hsa-mir-1343-5p ; hsa-mir-30a-5p ; hsa-mir-30b-5p ; hsa-mir-30c-5p ; hsa-mir-30d-5p ; hsa-mir-30e-5p ; hsa-mir-3607-5p ; hsa-mir-3613-3p ; hsa-mir-4330 ; hsa-mir-4419a ; hsa-mir-4510 ; hsa-mir-4739 ; hsa-mir-4756-5p ; hsa-mir-4790-3p ; hsa-mir-4802-5p ; hsa-mir-551b-5p ; hsa-mir-6081 ; hsa-mir-6127 ; hsa-mir-6129 ; hsa-mir-6130 ; hsa-mir-6133 ; hsa-mir-6515-5p ; hsa-mir-6783-5p ; hsa-mir-6797-5p ; hsa-mir-6799-5p ; hsa-mir-6824-5p ; hsa-mir-939-5p ; hsa-mir-942-5p

Nearest miRNA

hsa-mir-12113/Upstream/1511030; hsa-mir-1243/Downstream/6647254;

Nearest TSS

Nearest CpG islands

None/Target, chr4-CpG: 46/Upstream/13209, chr4-CpG: 51/Downstream/27393

Upstream sequence

tgctcaatcaaaagaaagtttaaactccgtgaattgaacgcacccatcacaaagtagtttctgagaatgattctgtctatattttatacgaagatatttc

Downstream sequence

TAAGTGAATATATTTTTCCAGTCATCAAGACTAAGATTCAGTATAATGGAGTCATCTTTGTCTTTCACCCTTCCCTTTCCTTATGAGTGTCCATTTCTAC