VISDB Viral Integration Site DataBase

VIS ID

TVIS10009419

Fusion event

HBV-AGO2 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

X protein|Polymerase|

Start

1612

Orient

+

Integrated sequence

GACCGACCACGGGGCGCACCTCTCTTTACGCGGACTCCCCGTCTGTGCCTTCTCATCTGCCGGACCGTGTGCACTTCGCTTCACCTCTGCACGTCGCATG| |GAGACCACCGTGAACGCCCACCAAATATTGCCCAAGGTCTTACATAAGAGGACTCTTGGACTCTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCA

Chromosome

chr8

Cytoband

q24.3

Reference genome

Start

End

141532035/140521936 (Hg38)

Orient

-

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-376a-3p ; hsa-mir-215-5p ; hsa-mir-192-5p ; hsa-mir-107 ; hsa-mir-99a-5p ; hsa-mir-21-5p ; hsa-mir-16-5p ; hsa-mir-671-5p ; hsa-mir-652-3p ; hsa-mir-186-5p ; hsa-mir-30d-5p ; hsa-mir-30a-5p ; hsa-let-7e-5p ; hsa-let-7b-5p ; hsa-let-7a-5p ; hsa-mir-3120-3p ; hsa-mir-3133 ; hsa-mir-184 ; hsa-mir-4795-3p ; hsa-mir-223-5p ; hsa-mir-5193 ; hsa-mir-3934-5p ; hsa-mir-764 ; hsa-mir-5002-5p ; hsa-mir-125a-3p ; hsa-mir-126-5p ; hsa-mir-548l ; hsa-mir-559 ; hsa-mir-548y ; hsa-mir-548o-5p ; hsa-mir-548w ; hsa-mir-548j-5p ; hsa-mir-548i ; hsa-mir-548h-5p ; hsa-mir-548d-5p ; hsa-mir-548bb-5p ; hsa-mir-548c-5p ; hsa-mir-548b-5p ; hsa-mir-548ay-5p ; hsa-mir-548au-5p ; hsa-mir-548as-5p ; hsa-mir-548ar-5p ; hsa-mir-548ap-5p ; hsa-mir-548aq-5p ; hsa-mir-548am-5p ; hsa-mir-548ak ; hsa-mir-548ae-5p ; hsa-mir-548ad-5p ; hsa-mir-548ab ; hsa-mir-6887-5p ; hsa-mir-548a-5p ; hsa-mir-6795-5p ; hsa-mir-7111-5p ; hsa-mir-6870-5p ; hsa-mir-5698 ; hsa-mir-8085 ; hsa-mir-4723-5p ; hsa-mir-6731-5p ; hsa-mir-4644 ; hsa-mir-4306 ; hsa-mir-185-5p ; hsa-mir-6133 ; hsa-mir-6129 ; hsa-mir-6130 ; hsa-mir-6127 ; hsa-mir-4510 ; hsa-mir-4419a ; hsa-mir-4524a-3p ; hsa-mir-6794-5p ; hsa-mir-4716-3p ; hsa-mir-4739 ; hsa-mir-4756-5p ; hsa-mir-1321 ; hsa-mir-6873-5p ; hsa-mir-4507 ; hsa-mir-3940-5p ; hsa-mir-6751-5p ; hsa-mir-6803-5p ; hsa-mir-7109-5p ; hsa-mir-4665-5p ; hsa-mir-6811-5p ; hsa-mir-1275 ; hsa-mir-6511b-5p ; hsa-mir-6793-5p ; hsa-mir-92a-1-5p ; hsa-mir-6769b-5p ; hsa-mir-92a-2-5p ; hsa-mir-6769a-5p ; hsa-mir-654-5p ; hsa-mir-541-3p ; hsa-mir-5010-5p ; hsa-mir-4525 ; hsa-mir-6878-5p ; hsa-mir-625-5p ; hsa-mir-1193 ; hsa-mir-4722-5p ; hsa-mir-1286 ; hsa-mir-6841-3p ; hsa-mir-873-5p ; hsa-mir-6895-5p ; hsa-mir-583 ; hsa-mir-6825-5p ; hsa-mir-3144-5p ; hsa-mir-6781-5p ; hsa-mir-6883-5p ; hsa-mir-6785-5p ; hsa-mir-4728-5p ; hsa-mir-149-3p ; hsa-mir-3649 ; hsa-mir-6797-5p ; hsa-mir-6077 ; hsa-mir-1249-5p ; hsa-mir-6836-5p ; hsa-mir-6132 ; hsa-mir-6889-5p ; hsa-mir-6777-5p ; hsa-mir-3918 ; hsa-mir-761 ; hsa-mir-3619-5p ; hsa-mir-214-3p ; hsa-mir-6822-5p ; hsa-mir-6750-5p ; hsa-mir-6165 ; hsa-mir-15a-5p ; hsa-mir-15b-5p ; hsa-mir-195-5p ; hsa-mir-424-5p ; hsa-mir-497-5p ; hsa-mir-6838-5p ; hsa-mir-3175 ; hsa-mir-6856-5p ; hsa-mir-6758-5p ; hsa-mir-8055 ; hsa-mir-8081 ; hsa-mir-627-5p ; hsa-mir-937-5p ; hsa-mir-4785 ; hsa-mir-6755-3p ; hsa-mir-3613-3p ; hsa-mir-5094 ; hsa-mir-944 ; hsa-mir-548c-3p ; hsa-mir-148b-3p ; hsa-mir-152-3p ; hsa-mir-148a-3p ; hsa-mir-374b-3p ; hsa-mir-4766-3p ; hsa-mir-6792-5p ; hsa-mir-4522 ; hsa-mir-646 ; hsa-mir-548p ; hsa-mir-3664-5p ; hsa-mir-590-5p ; hsa-mir-4799-5p ; hsa-mir-506-5p ; hsa-mir-6074 ; hsa-mir-892c-5p ; hsa-mir-103a-3p ; hsa-mir-491-3p ; hsa-mir-4509 ; hsa-mir-4699-3p ; hsa-mir-3680-3p ; hsa-mir-302c-5p ; hsa-mir-33b-5p ; hsa-mir-33a-5p ; hsa-mir-195-3p ; hsa-mir-16-2-3p ; hsa-mir-802 ; hsa-mir-3908 ; hsa-mir-4703-5p ; hsa-mir-3942-5p ; hsa-mir-7-2-3p ; hsa-mir-7-1-3p ; hsa-mir-3121-3p ; hsa-mir-548t-5p ; hsa-mir-548az-5p ; hsa-mir-548n ; hsa-mir-4744 ; hsa-mir-548e-5p ; hsa-mir-4666a-5p ; hsa-mir-548v ; hsa-mir-187-5p ; hsa-mir-222-3p ; hsa-mir-221-3p ; hsa-mir-95-5p ; hsa-mir-5688 ; hsa-mir-495-3p ; hsa-mir-4495 ; hsa-mir-5582-5p ; hsa-mir-4719 ; hsa-mir-4803 ; hsa-mir-5692a ; hsa-mir-548an ; hsa-mir-382-3p ; hsa-mir-124-3p ; hsa-mir-6763-5p ; hsa-mir-3150a-3p ; hsa-mir-6783-3p ; hsa-mir-1343-3p ; hsa-mir-939-5p ; hsa-mir-1343-5p ; hsa-mir-6827-5p ; hsa-mir-505-5p ; hsa-mir-8089 ; hsa-mir-4700-5p ; hsa-mir-4667-5p ; hsa-mir-6852-5p ; hsa-mir-6742-3p ; hsa-mir-939-3p ; hsa-mir-8064 ; hsa-mir-1911-5p ; hsa-mir-4682 ; hsa-mir-4653-5p ; hsa-mir-3921 ; hsa-mir-6777-3p ; hsa-mir-4714-5p ; hsa-mir-362-3p ; hsa-mir-329-3p ; hsa-mir-8485 ; hsa-mir-513b-5p ; hsa-mir-6837-3p ; hsa-mir-6754-3p ; hsa-mir-412-3p ; hsa-mir-145-3p ; hsa-mir-466 ; hsa-mir-4643 ; hsa-mir-576-5p ; hsa-mir-4263 ; hsa-mir-211-5p ; hsa-mir-204-5p ; hsa-mir-524-5p ; hsa-mir-520d-5p ; hsa-mir-31-3p ; hsa-mir-6832-3p ; hsa-mir-4328 ; hsa-mir-8054 ; hsa-mir-548k ; hsa-mir-548av-5p ; hsa-mir-578 ; hsa-mir-132-3p ; hsa-mir-1207-5p ; hsa-mir-1255a ; hsa-mir-1255b-5p ; hsa-mir-1298-3p ; hsa-mir-204-3p ; hsa-mir-3192-5p ; hsa-mir-3197 ; hsa-mir-3616-3p ; hsa-mir-3691-3p ; hsa-mir-3910 ; hsa-mir-4270 ; hsa-mir-4314 ; hsa-mir-4441 ; hsa-mir-4646-5p ; hsa-mir-4668-3p ; hsa-mir-4763-3p ; hsa-mir-510-3p ; hsa-mir-5187-5p ; hsa-mir-542-5p ; hsa-mir-602 ; hsa-mir-605-3p ; hsa-mir-6087 ; hsa-mir-6125 ; hsa-mir-619-5p ; hsa-mir-6506-5p ; hsa-mir-658 ; hsa-mir-6754-5p ; hsa-mir-6765-5p ; hsa-mir-6804-5p ; hsa-mir-6820-5p ; hsa-mir-8063 ; hsa-mir-92b-5p ; hsa-mir-10b-3p ; hsa-mir-181b-2-3p ; hsa-mir-181b-3p ; hsa-mir-2115-5p ; hsa-mir-2277-3p ; hsa-mir-34c-3p ; hsa-mir-3619-3p ; hsa-mir-3620-3p ; hsa-mir-3660 ; hsa-mir-3690 ; hsa-mir-4256 ; hsa-mir-4308 ; hsa-mir-4420 ; hsa-mir-4526 ; hsa-mir-4690-3p ; hsa-mir-4755-5p ; hsa-mir-4776-5p ; hsa-mir-5006-3p ; hsa-mir-504-5p ; hsa-mir-516a-3p ; hsa-mir-516b-3p ; hsa-mir-520a-3p ; hsa-mir-5685 ; hsa-mir-623 ; hsa-mir-6719-3p ; hsa-mir-6730-3p ; hsa-mir-6856-3p ; hsa-mir-7162-5p

Nearest miRNA

hsa-mir-1204/Upstream/5716991; hsa-mir-10400/Downstream/210628;

Nearest TSS

Nearest CpG islands

None/Target, chr8-CpG: 109/Upstream/9575, chr8-CpG: 18/Downstream/13486

Nearby gene

CHRAC1(-4783) ; AGO2(+9229) ;

Upstream sequence

CAGATCTTTGAAGACTAAAACGTTTTCCAGTCTCACAGGAAAAAAAATCAAATATTGAAAACGATAGGAGATGGGTTGATGTTTGACACACAGGAGATAA

Downstream sequence

TATAAATATGTGCATAGAGGAGTTTGGACTTTATTGTTTGTAAAATGTTAAATTTGCTCTTGGACATTTTTTTTTTTCTTTTCACAGGGGGGCAGTCGGG