SERBP1 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10009422
Fusion event
HBV-SERBP1 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
Polymerase|large S protein|
Start
3116
Orient
-
Integrated sequence
CACCCCACCGCACGGAGGCCTTTTGGGGTGGAGCCCTCAGGCTCAGGGCATACTACAAACTTTGCCAGCAAATCCGCCTCCTGCCTCCACCAATCGCCAG| |TCAGGAAGGCAGCCTACCCCGCTGTCTCCACCTTTGAGAAACACTCATCCTCAGGCCATGCAGTGG
Host Sequence
Chromosome
chr1
Cytoband
p31.3
Reference genome
End
67895434/67429751 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
Target gene
miRNAs that regulate target gene
hsa-mir-26a-5p ; hsa-mir-10a-5p ; hsa-mir-16-5p ; hsa-mir-93-3p ; hsa-mir-652-3p ; hsa-mir-625-5p ; hsa-mir-615-3p ; hsa-mir-505-3p ; hsa-mir-328-3p ; hsa-mir-374a-5p ; hsa-mir-30b-5p ; hsa-mir-15b-5p ; hsa-mir-100-5p ; hsa-mir-27a-3p ; hsa-mir-18a-5p ; hsa-let-7e-5p ; hsa-let-7b-5p ; hsa-mir-8485 ; hsa-mir-548n ; hsa-mir-4699-3p ; hsa-mir-6509-5p ; hsa-mir-6732-3p ; hsa-mir-450b-5p ; hsa-mir-6750-3p ; hsa-mir-6512-5p ; hsa-mir-433-3p ; hsa-mir-7154-5p ; hsa-mir-4443 ; hsa-mir-1273e ; hsa-mir-7847-3p ; hsa-mir-6880-5p ; hsa-mir-6799-5p ; hsa-mir-6851-5p ; hsa-mir-3689d ; hsa-mir-650 ; hsa-mir-3612 ; hsa-mir-6134 ; hsa-mir-6884-5p ; hsa-mir-485-5p ; hsa-mir-1827 ; hsa-mir-4649-3p ; hsa-mir-219b-3p ; hsa-mir-1247-3p ; hsa-mir-6511a-5p ; hsa-mir-1910-3p ; hsa-mir-2054 ; hsa-mir-302f ; hsa-mir-6803-5p ; hsa-mir-6751-5p ; hsa-mir-7109-5p ; hsa-mir-4665-5p ; hsa-mir-1275 ; hsa-mir-4799-5p ; hsa-mir-5010-5p ; hsa-mir-4525 ; hsa-mir-7111-5p ; hsa-mir-6870-5p ; hsa-mir-4723-5p ; hsa-mir-5698 ; hsa-mir-8059 ; hsa-mir-4471 ; hsa-mir-651-5p ; hsa-mir-4715-3p ; hsa-mir-885-5p ; hsa-mir-22-3p ; hsa-mir-6802-5p ; hsa-mir-6800-5p ; hsa-mir-4645-3p ; hsa-mir-4790-3p ; hsa-mir-622 ; hsa-mir-3177-5p ; hsa-mir-5093 ; hsa-mir-875-3p ; hsa-mir-4308 ; hsa-mir-511-3p ; hsa-mir-504-5p ; hsa-mir-1257 ; hsa-mir-8060 ; hsa-mir-664a-3p ; hsa-mir-4703-5p ; hsa-mir-3942-5p ; hsa-mir-548l ; hsa-mir-424-5p ; hsa-mir-195-5p ; hsa-mir-15a-5p ; hsa-mir-497-5p ; hsa-mir-6838-5p ; hsa-mir-7153-5p ; hsa-mir-146b-5p ; hsa-mir-146a-5p ; hsa-mir-589-5p ; hsa-mir-4501 ; hsa-mir-362-3p ; hsa-mir-329-3p ; hsa-mir-513a-5p ; hsa-mir-4733-3p ; hsa-mir-370-5p ; hsa-mir-4764-3p ; hsa-mir-510-5p ; hsa-mir-548t-3p ; hsa-mir-548ap-3p ; hsa-mir-548aa ; hsa-mir-548x-3p ; hsa-mir-548j-3p ; hsa-mir-548aq-3p ; hsa-mir-548am-3p ; hsa-mir-548aj-3p ; hsa-mir-548ah-3p ; hsa-mir-548ae-3p ; hsa-mir-548z ; hsa-mir-548h-3p ; hsa-mir-548d-3p ; hsa-mir-548bb-3p ; hsa-mir-548ac ; hsa-mir-4462 ; hsa-mir-6754-5p ; hsa-mir-4441 ; hsa-mir-4270 ; hsa-mir-211-3p ; hsa-mir-7845-5p ; hsa-mir-19b-3p ; hsa-mir-19a-3p
Nearest miRNA
hsa-mir-101-1/Upstream/801234; hsa-mir-11399/Downstream/753767;
Nearest CpG islands
chr1-CpG: 139/Target, None/Upstream, None/Downstream
Upstream sequence
TGCGCTCACCCGCCAAGGAATCCGGCGGGAAGGCAACAGCCTCCCAGGACCTCGAGCGCGCTCGAGGAGCAGCTCATCTCCGACCACGCTCCTCTGCTCA
Downstream sequence
CAACCTGAGGCGGGAAGGGGATGGCTCCGAGAACCTCGCCGGCGGTGGCTTGAACTTGGGGCTACCACGCTCCTGGCACCTTCGCAGGACCGGACTTTTG
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
Curate