VISDB Viral Integration Site DataBase

VIS ID

TVIS10009438

Fusion event

HBV-NCOA2 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

Polymerase|

Start

2713

Orient

+

Integrated sequence

TGAGAAAAGAAGATTGCAATTGATTATGCCTGCCAGGTTTTATCCAAAGGTTACCAAATATTTACCATTGGATAAGGGTATTAAACCTTATTATCCAGAA| |CATCTAGTTAATCATTACTTCCAAACTAGACACTATTTACACACTCTATGGAAGGCGGGTATATTATATAAGAGAGAAACAACACATAGCGCCTCATTTT

Chromosome

chr8

Cytoband

q13.3

Reference genome

Start

End

71126934/70214699 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-137 ; hsa-mir-193b-3p ; hsa-mir-544a ; hsa-mir-1185-5p ; hsa-mir-6864-5p ; hsa-mir-4471 ; hsa-mir-8059 ; hsa-mir-539-5p ; hsa-mir-3179 ; hsa-mir-7515 ; hsa-mir-6822-5p ; hsa-mir-6750-5p ; hsa-mir-3120-3p ; hsa-mir-429 ; hsa-mir-200b-3p ; hsa-mir-200c-3p

Nearest miRNA

hsa-mir-124-1/Upstream/5835442; hsa-mir-10400/Downstream/4333844;

Nearest TSS

Nearest CpG islands

None/Target, chr8-CpG: 109/Upstream/142046, chr8-CpG: 251/Downstream/187211

Upstream sequence

CTTCCAAAGCAGCCTTTCCTCCTTCAGCCACTGCCCGTCACATCACCGTATTATTTTATAAGATTCTTCTCATAACTTTGCTTTTTTTACTTATTTATTG

Downstream sequence

CAGTCCAATTTCAACTAAAGTTTAAAAAGTTAATGGAATGGAAAAATATCAAAAGAGGCAAAATCTTCCATTAGAATGTGACAAAATAGTAAACTGAAAA